Titans vs Cardinals Preview: Week 5 Desperation Bowl
Opening Setup
Here’s what we’ve got in Week 5: the winless Tennessee Titans traveling to Arizona to face a Cardinals team that’s dropped two straight heartbreakers. If you’re new to betting, this is what we call a “desperation game” — both teams need this win badly, but for completely different reasons. Tennessee is trying to avoid an 0-5 start that could torpedo their season, while Arizona wants to get back on track in a competitive NFC West.
The betting market is telling us a clear story here. Arizona opened as 7.5-point favorites and that number has ballooned to 9.5 points at most books. When you see line movement like that — especially going against the typical “bet the dog” public mentality — it usually means the sharp money is hammering the favorite. Let’s break down why the market thinks the Cardinals should win by double digits.
Game Details Box
Date: Sunday, October 5
Time: 4:05 PM ET
Location: State Farm Stadium, Glendale
TV: CBS
Current Betting Lines
| Bet Type | Line | Juice |
|---|---|---|
| Point Spread | Arizona -7.5 | -110 |
| Total Points | Over/Under 41 | Over -115 / Under -105 |
| Moneyline | Arizona -450 / Tennessee +335 | – |
Quick Translation: Arizona needs to win by 8+ points to cover the spread. The total means you’re betting whether both teams combine for more or less than 41 points. The moneyline shows Arizona is heavily favored — you’d need to bet $450 to win $100 on the Cardinals, while $100 on Tennessee pays $335.
Line Movement Analysis
The line opened at Tennessee +7.5 and has moved to +9.5 at most books — that’s significant movement in the wrong direction for the underdog. In betting terms, this is called “reverse line movement.” Normally when a line moves against the public dog, it signals that sharp bettors are backing the favorite heavily. The slight juice favor on the under (-105 vs -115 on the over) suggests the market expects a lower-scoring affair, which makes sense given Tennessee’s offensive struggles.
Key Matchups
The game will likely be decided by Tennessee’s ability to protect rookie quarterback Cam Ward. The Titans have already given up a league-high 17 sacks through four games, while Ward is completing just 51.2% of his passes. Arizona’s defense ranks 5th in scoring defense at 18.5 points per game and owns a top-10 sack rate that could make life miserable for a rookie signal caller.
On the other side, Tennessee’s defense hasn’t been much better. The Titans are giving up 27.5 points per game, with opponents converting nearly 43% of third downs and cashing in on red zone chances at an alarming rate. That’s a recipe for Kyler Murray and rookie wideout Marvin Harrison Jr. to keep moving the chains, especially if Harrison builds on last week’s 6-catch, 66-yard performance.
Why Smart Bettors Like Arizona
- Massive talent gap — Cardinals simply have better players at nearly every position.
- Home field advantage — Arizona is 10-5 ATS in their last 15 games overall.
- Titans’ road struggles — Tennessee is 0-6 ATS in their last six games against NFC opponents.
Betting Recommendations
Primary Bet: Under 41 Total Points — Tennessee has scored just 51 points in four games (12.8 per game), dead last in the league. Arizona’s defense has been stingy, but their offense hasn’t exactly been lighting up the scoreboard either. Both teams have struggled to finish drives in the red zone, and this projects as a grind-it-out contest. Think 24-10 or 21-13, both landing safely under the number.
Secondary Consideration: If you must play the spread, Arizona -7.5 is more palatable than -9.5. But nine points is a lot to lay on any NFL team, especially one that’s lost two straight games.
What to Watch For
- Live betting opportunities if Tennessee keeps it close early
- Cam Ward’s mobility — can he escape pressure and extend plays
- Arizona’s red zone efficiency — defense has been excellent, but offense must cash in drives
- Weather conditions in Glendale — dome game eliminates variables
Bottom Line Summary
This is a classic “good team vs bad team” spot where the market is essentially daring you to take the winless dog. While Tennessee is clearly inferior, nine points is a massive number in the NFL. The better value appears to be on the total, where Tennessee’s offensive ineptitude and Arizona’s red zone volatility both point squarely to the under. Arizona should win, but they’ll have to do it the hard way against a desperate team.
Final Score Prediction: Arizona 24, Tennessee 13.


