College Football Picks

Duke at Miami picks: the Canes are laying 13.5 without Malachi Toney, and Manny Diaz’s defense plus Nate Sheppard make that a lot of points to give.

Ole Miss is a 1.5-point road favorite in Norman, but the bet we like in this Ole Miss vs Oklahoma prediction is the total, not either side.

Michigan at Oregon prediction: the Ducks are laying 11.5 to a Wolverines team in offensive chaos, but Michigan’s defense has kept every game close.

The market dropped this Alabama vs Vanderbilt line four points on Keelon Russell’s ankle. Our prediction says the Commodores’ turnover habit makes that a gift.

Our USC vs Indiana prediction: the Hoosiers are -7.5 with a 50.5 total, and with Indiana’s QB room unsettled and its defense suffocating, the number is too high.

Two backup quarterbacks, a noon kick and two Big Ten defenses. Our Northwestern vs Ohio State prediction plays the total, not the 12.5-point spread.

Wake Forest vs SMU prediction: the line flipped from Deacons -2.5 to Mustangs -1.5, and with Gio Lopez set to return, that move looks like a gift.

Texas Tech vs Oklahoma State prediction: the 8-1 Red Raiders catch points in Stillwater, but Drew Mestemaker against a leaky secondary is the story.

South Carolina at Arkansas prediction: the Gamecocks are laying 7.5 with Georgia up next and Sellers nursing an ankle. Here’s why I’m taking the hook.

Our Purdue vs Iowa prediction: the Hawkeyes are -16.5 with a 47.5 total, and a Purdue defense that just fired its coordinator is walking into a buzzsaw.