Northwestern vs. USC Pick: Can the Winless Wildcats Stun the Trojans?

by | Jan 21, 2026 | cbb

Ezra Ausar USC Trojans

Despite a 0-7 start in Big Ten play, Northwestern remains one of the nation’s most disciplined teams, ranking 1st in the conference in turnovers per game. This best bet explores if their ball security can keep them within the 6-point spread against an injury-plagued USC roster.

The Setup: Northwestern at USC

USC’s laying 5.5 to 6 points at home against Northwestern on Tuesday night, and this spread tells you everything about how the market views these two Big Ten squads right now. The Trojans sit at 8-1 while the Wildcats have dropped five straight, but here’s what matters: when you dig into the collegebasketballdata.com efficiency numbers, this line isn’t about records—it’s about Northwestern’s complete inability to defend anybody right now. USC ranks 28th nationally in adjusted offensive efficiency at 118.9, and they’re facing a Northwestern defense that checks in at 202nd in defensive rating. The Trojans should eat in this spot, and the market knows it.

Northwestern’s adjusted defensive efficiency sits at 104.6, which ranks 110th nationally—not terrible on paper. But that’s the full-season number. Over their last five games, they’ve allowed 76, 79, 77, 76, and 84 points while facing quality Big Ten competition. They can’t get stops when they need them, and USC’s got the offensive firepower to exploit every crack in that defense.

Game Info & Betting Lines

Game: Northwestern (5-4) @ USC (8-1)
Date: January 21, 2026
Time: 11:00 PM ET
Location: Galen Center, Los Angeles, CA
Type: Big Ten Conference Game

Bovada Spread: USC -6
DraftKings Spread: USC -5.5
Total: 153-153.5
Moneyline: USC -270, Northwestern +220

Why This Number Makes Sense (or Doesn’t)

Let’s start with the efficiency math that explains this spread. USC’s adjusted net rating sits at 13.1 (52nd nationally), while Northwestern checks in at 11.8 (60th). That’s basically a push in terms of overall quality. But here’s where the line gets justified: home court advantage typically adds 3-4 points, and more importantly, Northwestern’s current form is absolutely brutal. Five straight losses, and they haven’t looked competitive in any of them.

The total at 153 to 153.5 makes perfect sense when you consider the pace and efficiency metrics. Northwestern plays at 68.1 possessions per game (196th nationally), while USC pushes it slightly faster at 69.6 (143rd). Neither team plays at a breakneck pace, but both offenses rank in the top 80 nationally in offensive rating—Northwestern at 119.5 (77th) and USC at 119.4 (79th). When you’ve got two efficient offenses and Northwestern’s porous defense, you’re looking at a game that should push toward the mid-150s.

The market landed on USC -5.5 to -6 because it’s accounting for Northwestern’s defensive struggles while also respecting that the Wildcats can still score. Northwestern ranks 50th in adjusted offensive efficiency at 116.4, and they shoot 50% from the field (35th nationally). They’re not going to roll over offensively—they just can’t stop anybody on the other end.

Northwestern Breakdown: The Analytical Edge

Northwestern’s offense remains their calling card, and Nick Martinelli is the engine that makes it go. The forward is averaging 21.1 points per game (13th nationally) and provides legitimate scoring punch. Arrinten Page adds 15.4 points and 7.1 rebounds, giving the Wildcats a second reliable option. The real strength here is ball security—Northwestern ranks 25th nationally in turnovers per game at just 9.8, and their turnover ratio of 0.1 ranks 17th. They take care of the basketball.

The shooting numbers back up their offensive efficiency. Northwestern’s effective field goal percentage sits at 55.7% (70th nationally), and their true shooting percentage of 60.0% ranks 66th. They also rank 33rd in assists per game at 18.3, which tells you they’re moving the ball and getting quality looks. Guard Jayden Reid is the facilitator, dishing out 5.9 assists per game (30th nationally).

But here’s the problem: none of that offensive prowess matters when you can’t defend. Northwestern’s defensive rating of 107.2 ranks 202nd, and opponents are shooting 41.5% against them. The rebounding is atrocious—they rank 295th in rebounds per game at just 33.7 and 271st in offensive rebound percentage. They’re getting killed on the glass and can’t create second-chance opportunities.

USC Breakdown: The Counterpoint

USC’s got the offensive firepower to blow this game open, and it starts with their one-two punch of Chad Baker-Mazara and Rodney Rice. Baker-Mazara averages 20.9 points per game (18th nationally), while Rice chips in 20.3 points (28th nationally) and 6.0 assists per game (24th). That’s elite production from your top two guys, and both can create their own shot or facilitate for others.

The Trojans rank 28th nationally in adjusted offensive efficiency at 118.9, and they’ve got the shooting to back it up. USC hits 37.8% from three-point range (36th nationally), which forces defenses to respect the perimeter. They also rank 5th nationally in blocks per game at 6.6, which means they protect the rim better than almost anybody in the country. That rim protection is going to be crucial against Northwestern’s paint-heavy attack.

Where USC gets vulnerable is their defense overall. They rank 137th in adjusted defensive efficiency at 105.8, and they allow 78.2 points per game (278th nationally). They’ve also got turnover issues, coughing it up 11.9 times per game (153rd). But here’s the thing: Northwestern doesn’t force turnovers. The Wildcats rank 286th in steals per game at just 5.9. They’re not built to capitalize on USC’s ball-handling mistakes.

The Matchup: Where This Gets Decided

This game comes down to whether Northwestern can survive USC’s offensive onslaught at the Galen Center. The Trojans score 89.0 points per game (26th nationally), and they’re facing a Northwestern defense that’s allowed 76-plus points in four of their last five games. The pace won’t be frenetic—both teams rank outside the top 140 nationally in tempo—but the efficiency gap on defense is massive.

Northwestern’s rebounding deficiency is going to get exposed. USC ranks 156th in offensive rebound percentage at 31.7%, which isn’t elite, but against a Northwestern team that ranks 271st in offensive rebounding, the Trojans should control the glass. That means more possessions and more opportunities for Baker-Mazara and Rice to operate.

The three-point shooting matchup favors USC as well. Northwestern defends the three reasonably well—opponents shoot just 29.2% from deep (51st nationally)—but USC’s got legitimate shooters who can stretch the floor. And when Northwestern’s forced to defend in space, their lack of athleticism and rim protection (183rd in blocks per game at 3.4) becomes a problem.

The one area where Northwestern can stay competitive is ball security. They don’t turn it over, and USC doesn’t force turnovers. That should keep the game from getting completely out of hand, but it doesn’t solve Northwestern’s fundamental problem: they can’t stop USC from scoring.

Bash’s Best Bet

I’m laying the points with USC at -5.5. Northwestern’s five-game losing streak isn’t a fluke—they’re getting exposed defensively against quality Big Ten competition, and USC’s got the offensive firepower to exploit every weakness. The Trojans rank 28th nationally in adjusted offensive efficiency, and they’re facing a defense that ranks 202nd in defensive rating. That’s a mismatch.

The total at 153.5 is tempting because Northwestern can score, but I trust USC’s ability to get stops more than I trust Northwestern’s. The Trojans rank 5th nationally in blocks per game, and that rim protection should slow down Northwestern’s interior attack just enough to keep this game in the mid-150s range. Give me USC -5.5 and feel good about it. The Trojans win this one by double digits at home.

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