Brewers vs Cubs Prediction & Best Bets | NL Central Rivals Clash at Wrigley

by | Aug 18, 2025 | mlb

Brewers vs Cubs Prediction & Best Bets | NL Central Rivals Clash at Wrigley

The Milwaukee Brewers (77-45) head to Wrigley Field for a pivotal five-game series against the Chicago Cubs (70-53), beginning with Monday’s doubleheader. Despite Milwaukee’s 14-game winning streak finally ending Sunday with a 3-2 extra-inning loss to Cincinnati, they’ve established an eight-game lead in the NL Central. This matchup features two of the NL’s top pitchers in the opener with Freddy Peralta facing rookie sensation Cade Horton. With Chicago desperately needing to gain ground and Milwaukee looking to maintain their momentum, this series opener sets the stage for what could be the most significant NL Central showdown of the season.

Quick Picks:

  • Best Bet: Milwaukee Brewers Moneyline (+108) ★★★★☆
  • Top Prop: Freddy Peralta Over 6.5 Strikeouts (-115) ★★★★☆
  • Value Play: Total Under 8.5 (-115) ★★★☆☆

Milwaukee Brewers vs Chicago Cubs Betting Odds & Latest Line Movement

Market Milwaukee Brewers Chicago Cubs
Moneyline +108 -130
Run Line +1.5 (-195) -1.5 (+165)
Total Over 8.5 (-105) Under 8.5 (-115)

Opening Line: Cubs -125, Total 8.5

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The market has moved slightly in Chicago’s favor, from -125 to -130, suggesting some professional action on the home team. However, I’m seeing value on the Brewers side at the current price. The total has held steady at 8.5, with a slight juice adjustment toward the under, which aligns with Wrigley Field’s reputation as one of the more pitcher-friendly parks this season (0.898 run factor, 25th in MLB). This pitching matchup features two excellent starters who have been dominant recently, further explaining the sharp money leaning toward the under.

Pitching Matchup: Freddy Peralta vs Cade Horton – Who Has the Edge?

Milwaukee Brewers: Freddy Peralta (14-5, 2.90 ERA)

  • Leading the league with 14 wins and maintaining an impressive 2.90 ERA over 136.2 innings
  • Elite strikeout production with 148 Ks (9.7 K/9) and solid 1.12 WHIP
  • Recent success with just one run allowed and 14 strikeouts across 11 innings in his last two starts
  • Strong career numbers against Chicago: 8-3 with a 3.42 ERA in 21 appearances (16 starts)

Chicago Cubs: Cade Horton (7-3, 3.07 ERA)

  • Outstanding rookie campaign with 3.07 ERA and 67 strikeouts over 85 innings
  • Nearly untouchable since the All-Star break: 0.32 ERA in 28.1 innings with opponents hitting just .120
  • Only one extra-base hit allowed (a double) in his last five starts
  • First career appearance against Milwaukee adds uncertainty factor

Advantage: Slight edge to Peralta based on experience and track record, though Horton’s recent performance has been other-worldly. Peralta’s extensive success against the Cubs gives him a small advantage in this particular matchup.

Bullpen Breakdown

Milwaukee’s bullpen has been a significant strength this season, anchored by closer Trevor Megill (29 saves) and setup man Abner Uribe (league-leading 32 holds). The Brewers’ relief corps has posted a 3.85 ERA (12th in MLB), which is solid if not spectacular. Their depth with Nick Mears, Shelby Miller, and Jared Koenig provides manager Pat Murphy with multiple high-leverage options.

Chicago counters with closer Daniel Palencia (16 saves, 1.85 ERA) and quality setup options in Caleb Thielbar (2.23 ERA) and Brad Keller (2.48 ERA). The Cubs’ bullpen has been slightly more effective with a 3.81 ERA (11th), and their deadline additions of Andrew Kittredge and Taylor Rogers have strengthened their late-inning options.

While the Cubs’ bullpen has slightly better overall numbers, the Brewers’ relief corps has more experience handling high-leverage situations during their impressive winning streak. This creates a marginal advantage for Milwaukee in close, late-game situations.

Key Betting Trends & Team Statistics That Matter

  • Milwaukee’s offense ranks 2nd in runs scored (638) and 2nd in stolen bases (135), demonstrating their multi-dimensional attack
  • Chicago has been dominant at home with a 41-21 record at Wrigley Field this season
  • The Brewers had won 14 straight games before Sunday’s loss, showcasing their exceptional current form
  • Cubs have struggled offensively in August, scoring just 35 runs in 12 games (29th in MLB)
  • Milwaukee has the 3rd-best team ERA in baseball at 3.59, including a stellar 3.41 mark from their starters
  • Chicago is 7-8 in August and hasn’t gained ground in the standings since July 30
  • The Cubs’ Kyle Tucker is mired in a deep slump, batting just .200 with a .635 OPS since the All-Star break

Christian Yelich: Milwaukee’s MVP Candidate Fueling Their Success

Christian Yelich has been the offensive catalyst for Milwaukee’s success this season, slashing .267/.345/.467 with 25 homers, 86 RBIs, and 15 stolen bases. His “don’t-give-a-darn” attitude, as he recently described it, has permeated throughout the clubhouse and contributed to the Brewers’ relaxed approach during their historic winning streak. Yelich’s ability to produce in clutch situations will be crucial in this series, especially against a Cubs team desperate to gain ground in the division race.

The former MVP has found his power stroke again this season after a couple of down years, and his all-around production has been reminiscent of his 2018-2019 peak. With William Contreras heating up recently (including a clutch two-run homer in Sunday’s game), the Brewers’ offensive core presents significant challenges for Chicago’s pitching staff.

Wrigley Field Factor: How the Venue Influences Today’s Game

Wrigley Field has surprisingly played as one of the most pitcher-friendly venues in baseball this season, ranking 25th in run factor (0.898) and 24th in home run factor (0.883). This represents a significant departure from its traditional reputation as a hitter-friendly park. The afternoon start time (2:20 PM ET) further benefits pitchers, as the shadows between the mound and home plate often make it difficult for hitters to pick up spin.

Today’s weather forecast calls for temperatures around 80°F with winds blowing in from right field at 8-10 mph, creating even more favorable conditions for pitchers. These factors, combined with two excellent starting pitchers, suggest runs could be at a premium in this opener, supporting the under as a strong consideration.

Expert Prediction & Best Bets for Brewers-Cubs Showdown

Primary Play: Milwaukee Brewers Moneyline (+108)

I’m backing the Brewers as slight underdogs in this series opener despite their streak ending yesterday. Freddy Peralta has been among the NL’s best pitchers this season and has consistently performed well against the Cubs throughout his career. While Cade Horton has been exceptional lately, his lack of experience against Milwaukee’s potent lineup and the pressure of this crucial series could be factors. The Cubs’ offensive struggles in August (just 35 runs in 12 games) further strengthen the case for Milwaukee, who still possess the momentum from their recent 14-game streak. At plus-money odds, the Brewers offer excellent value.

Strong Value Play: Total Under 8.5 (-115)

This matchup screams under with two dominant starting pitchers, Wrigley Field playing as a pitcher’s park, favorable weather conditions, and the Cubs’ struggling offense. Peralta has allowed just one run in his last 11 innings, while Horton has been nearly untouchable since the All-Star break with a microscopic 0.32 ERA. The Cubs’ offensive struggles combined with the Brewers potentially experiencing a slight letdown after their streak ended create perfect conditions for a low-scoring affair. I’d play this under down to 8 runs.

Worth Considering: Freddy Peralta Over 6.5 Strikeouts (-115)

Peralta’s strikeout prop offers significant value given his track record against the Cubs (125 Ks in 92 career innings) and Chicago’s recent propensity to strike out. He’s recorded at least 7 strikeouts in 15 of his 25 starts this season, including 8 of his last 12 outings. With the Cubs struggling at the plate and Peralta’s swing-and-miss stuff, he should clear this number with room to spare.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Freddy Peralta Over 6.5 Strikeouts -115 ★★★★☆
Christian Yelich To Record a Hit -240 ★★★★☆
William Contreras Over 1.5 Total Bases +120 ★★★☆☆
Pete Crow-Armstrong Under 0.5 RBI -175 ★★★☆☆
Kyle Tucker Under 1.5 Total Bases -130 ★★★★☆

Final Thoughts: Brewers’ Momentum Trumps Cubs’ Desperation

While the Cubs have home-field advantage and a slightly better bullpen, Milwaukee’s superior starting pitching, offensive production, and overall momentum make them the value side in this matchup. Chicago’s struggles at the plate are particularly concerning against a pitcher of Peralta’s caliber. Even though their historic winning streak is over, the Brewers remain baseball’s most complete team and should be favored in this matchup despite what the odds suggest.

The first game of this five-game series sets the tone for what could be a season-defining week for both clubs. While desperation sometimes fuels strong performances, consistency and confidence typically win out in baseball’s long season. The Brewers have both in abundance right now, which is why I’m backing them as road underdogs.

Score Prediction: Milwaukee Brewers 4, Chicago Cubs 2

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