Brewers vs Cubs Prediction & Best Bets | Exciting NL Central Showdown at Wrigley

by | Jun 19, 2025 | mlb

Jameson Taillon Chicago Cubs

The Milwaukee Brewers (39-35) and Chicago Cubs (45-28) square off in a pivotal NL Central matchup at Wrigley Field today. The Cubs have been one of the hottest teams in baseball, extending their division lead to 6.5 games over the second-place Brewers. After Wednesday’s rainout, this afternoon tilt features a fascinating pitching matchup between Milwaukee’s promising rookie Jacob Misiorowski and Chicago’s consistent veteran Jameson Taillon. I’ve identified several key advantages for the Cubs that should translate to the betting window in what promises to be an entertaining finale to this series.

Quick Picks:

  • Best Bet: Cubs Moneyline (-145) ★★★★☆
  • Top Prop: Pete Crow-Armstrong Over 1.5 Total Bases (+115) ★★★★★
  • Value Play: Game Total Over 8.5 Runs (-110) ★★★☆☆

Brewers vs Cubs Betting Odds & Latest Line Movement

Market Milwaukee Brewers Chicago Cubs
Moneyline +125 -145
Run Line +1.5 (-155) -1.5 (+135)
Total Over 8.5 (-110) Under 8.5 (-110)

Opening Line: Cubs -140, Total 8

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

Early movement on this line has pushed slightly toward the Cubs, moving from -140 to -145, which suggests moderate professional interest on the home favorite. More telling is the total, which has ticked up from 8 to 8.5 despite Wrigley Field not showing extreme hitter-friendly conditions in the forecast. Professional bettors seem to be factoring in the Cubs’ potent offense against a rookie pitcher making only his second career start, along with the Brewers’ inconsistent bullpen that might be taxed after the recent doubleheader against the White Sox.

Pitching Matchup: Jacob Misiorowski vs Jameson Taillon – Who Has the Edge?

Milwaukee Brewers: Jacob Misiorowski (1-0, 0.00 ERA)

  • Impressive MLB debut, pitching 5 scoreless innings against the Cardinals
  • Electric fastball that touches 100 mph with a devastating slider
  • Limited professional experience could be exploited by patient Cubs lineup
  • Control issues evident with 4 walks in his debut outing

Chicago Cubs: Jameson Taillon (7-3, 3.48 ERA)

  • Exceptional command with just 16 walks in 82.2 innings this season
  • Impressive 0.98 WHIP shows his ability to limit baserunners
  • Has pitched at least 6 innings in 7 of his last 8 starts
  • Holds a 2.95 ERA at Wrigley Field this season

Advantage: Cubs. While Misiorowski has electric stuff, Taillon’s consistency, command, and experience give Chicago a significant edge, especially at home where he’s been particularly effective.

Bullpen Breakdown

The Cubs’ bullpen has been nothing short of spectacular lately, with three pitchers currently riding streaks of 15+ games without allowing an earned run (Drew Pomeranz, Caleb Thielbar, and Ryan Pressly). This trio gives manager Craig Counsell multiple high-leverage options to navigate the late innings. Daniel Palencia has emerged as the closer with 7 saves and a 1.67 ERA.

Milwaukee’s bullpen has been solid but less consistent, led by closer Trevor Megill (15 saves) and setup man Abner Uribe (19 holds, league-leading). The Brewers’ relief corps could be somewhat taxed after recent doubleheader usage, and they’ve been more vulnerable on the road this season with a 4.35 ERA away from American Family Field.

Key Betting Trends & Team Statistics That Matter

  • The Cubs are 26-11 at Wrigley Field this season, one of the best home records in MLB
  • Milwaukee is just 18-20 on the road and has struggled against teams over .500 (15-22)
  • Chicago has outscored opponents by 107 runs this season compared to just +19 for Milwaukee
  • The Cubs average 5.34 runs per game (4th in MLB) while the Brewers average just 4.31
  • Chicago has dominated the head-to-head matchup, winning 7 of the last 9 meetings
  • Pete Crow-Armstrong is batting .342 with 8 home runs with runners in scoring position

Pete Crow-Armstrong Spotlight: MLB’s Breakout Star Leading the Way

Chicago’s Pete Crow-Armstrong has emerged as one of baseball’s most exciting young stars, currently leading all NL outfielders in All-Star voting. His combination of elite defense, power (19 homers), and speed (23 stolen bases) makes him a dynamic threat in every facet of the game. PCA is currently on a tear, homering in Tuesday’s game while making a spectacular diving catch. His ability to hit pitches all over (and outside) the zone makes him particularly dangerous against a young pitcher like Misiorowski who may struggle with command.

Wrigley Field Factor: How the Venue Influences Today’s Game

Wrigley Field has played fairly neutral this season, but the Cubs’ familiarity with their home ballpark gives them a definite edge. The Brewers struggle with the unique dimensions and wind patterns at Wrigley, particularly their outfielders who don’t have the same read on the ivy-covered walls. Today’s afternoon start (2:20 pm ET) features moderate temperatures around 75 degrees with winds blowing in from right field at 8-10 mph – conditions that slightly favor pitchers but won’t completely neutralize power hitters.

Expert Prediction & Best Bets for Brewers-Cubs Showdown

Primary Play: Cubs Moneyline (-145) – 2 Units

I’m backing the Cubs as my strongest play today. Taillon’s consistency and command give Chicago a significant advantage over Misiorowski, who despite his talent, is making just his second MLB start. The Cubs’ home dominance (26-11), superior offense (5.34 runs/game), and lockdown bullpen create a perfect storm against a Brewers team that’s been mediocre on the road. Laying -145 offers solid value given the talent disparity, and I’d play this up to -155.

Strong Value Play: Pete Crow-Armstrong Over 1.5 Total Bases (+115)

Crow-Armstrong has been scorching hot, demonstrating an uncanny ability to hit pitches all over the zone. His combination of power and speed makes this one of my favorite props on the board. Facing a rookie pitcher who walked four batters in his debut, PCA should get pitches to drive as Misiorowski works to establish command. At plus-money odds, this offers exceptional value considering Crow-Armstrong has exceeded this total in 8 of his last 12 games.

Worth Considering: Game Total Over 8.5 Runs (-110)

While Wrigley’s conditions aren’t extremely hitter-friendly today, there are factors pointing to a higher-scoring affair. Misiorowski’s control issues could lead to extra baserunners for a Cubs lineup that capitalizes on mistakes. The Brewers have enough pop to damage Taillon’s occasional mistakes with the long ball. Both teams have reached this total in 7 of their last 10 meetings, and I expect the trend to continue today.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Pete Crow-Armstrong Over 1.5 Total Bases +115 ★★★★★
Jameson Taillon Over 5.5 Strikeouts -120 ★★★★☆
Seiya Suzuki To Record an RBI +140 ★★★☆☆
Jacob Misiorowski Under 4.5 Strikeouts -125 ★★★★☆

Final Thoughts: Cubs’ Home Dominance Continues

The combination of Taillon’s consistency, Chicago’s explosive offense led by Crow-Armstrong, and their nearly untouchable bullpen gives the Cubs clear advantages across the board. While Misiorowski has exciting potential, asking a rookie to navigate one of baseball’s most potent lineups in his second career start is a tall order. The Brewers will remain competitive in the division race, but today belongs to the Cubs as they continue their impressive home dominance and extend their NL Central lead.

Score Prediction: Cubs 6, Brewers 3

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