Diamondbacks vs Tigers Prediction & Best Bets | Mize Looks to Extend Detroit’s Winning Streak

by | Jul 29, 2025 | mlb

The Detroit Tigers (62-46) aim to build on their recent momentum as they host the struggling Arizona Diamondbacks (51-56) in the second game of their three-game series at Comerica Park. After securing a 5-1 victory in Monday’s opener, the Tigers look to make it three straight wins behind Casey Mize, who has been brilliant at home this season. The Diamondbacks, meanwhile, need to jumpstart an offense that broke a 34-inning streak without an earned run in Monday’s loss. With trade deadline rumors swirling around key Diamondbacks players, this matchup offers several intriguing betting opportunities.

Quick Picks:

  • Best Bet: Detroit Tigers Moneyline (-125) ★★★★☆
  • Top Prop: Casey Mize Over 5.5 Strikeouts (+100) ★★★★☆
  • Value Play: Under 8.5 Runs (-110) ★★★☆☆

Arizona Diamondbacks vs Detroit Tigers Betting Odds & Latest Line Movement

Market Arizona Diamondbacks Detroit Tigers
Moneyline +105 -125
Run Line +1.5 (-160) -1.5 (+140)
Total Over 8.5 (-110) Under 8.5 (-110)

Opening Line: Tigers -120, Total 8.5

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The slight movement from Tigers -120 to -125 indicates steady action on the home team, which makes sense given Detroit’s strong performance at home and Arizona’s offensive struggles. Sharp money appears to be favoring Detroit, particularly after their dominant pitching performance in Monday’s opener. While the total has remained steady at 8.5, there’s been some under money flowing in, likely reflecting both teams’ recent pitching success and Arizona’s anemic offense that has scored just 9 runs in their last 7 games. Professional bettors seem to be respecting Mize’s home dominance, where he’s been significantly better than his overall numbers suggest.

Pitching Matchup: Brandon Pfaadt vs Casey Mize – Who Has the Edge?

Arizona Diamondbacks: Brandon Pfaadt (10-6, 4.76 ERA)

  • Has been inconsistent on the road with a 5.42 ERA away from Chase Field
  • Strong K/BB ratio (95:25) indicates better performance than ERA suggests
  • Has allowed 19 home runs in 111.2 innings (1.53 HR/9), a major concern
  • Coming off a solid outing against Pittsburgh (6.1 IP, 2 ER), but struggled in previous two starts

Detroit Tigers: Casey Mize (9-4, 3.40 ERA)

  • Has been exceptional at Comerica Park with a 2.87 ERA in 11 home starts
  • 82 strikeouts to just 23 walks shows excellent command (3.57 K/BB ratio)
  • Limiting hard contact with just 13 home runs allowed in 92.2 innings
  • Coming off 7 scoreless innings against Toronto, looking increasingly confident

Advantage: Detroit Tigers. Mize has been significantly more consistent, especially at home, while Pfaadt’s road struggles and tendency to give up the long ball are concerns against a Tigers lineup that’s finding its rhythm.

Bullpen Breakdown

The Tigers’ bullpen has stabilized after some midseason struggles, with Will Vest (16 saves) and Tommy Kahnle (9 saves) forming a reliable late-inning duo. Monday’s performance was particularly encouraging, with Kahnle and Vest combining for 2 scoreless innings to close out the win. The Diamondbacks’ bullpen has been a revolving door of closer options, with Shelby Miller leading the team with just 10 saves. Their relief corps ranks in the bottom third of MLB with a 4.38 ERA. Kyle Backhus was impressive in Monday’s game with three strikeouts in one inning, but the overall edge clearly belongs to Detroit, which has more defined roles and better recent performance. The Tigers’ bullpen has posted a 3.21 ERA over the past two weeks compared to Arizona’s 4.75 mark.

Key Betting Trends & Team Statistics That Matter

  • The Tigers are 35-21 at Comerica Park this season, making them one of the best home teams in the American League
  • Arizona is just 21-31 on the road and has lost 7 of their last 9 away games
  • The Diamondbacks have scored just 9 runs total in their last 7 games
  • Casey Mize is 6-1 with a 2.87 ERA in his 11 home starts this season
  • Detroit has won 6 of Mize’s last 7 home starts
  • The Tigers are 18-8 in their last 26 interleague games against teams with losing records
  • The under is 7-2-1 in Arizona’s last 10 road games
  • Detroit starters have thrown 21 consecutive scoreless innings, a feat not accomplished by the franchise since 1949

Eugenio Suárez Trade Watch: Impact on Diamondbacks’ Lineup

All eyes will be on Eugenio Suárez’s availability for Tuesday’s game after he was hit on the hand by a 96 mph fastball in Monday’s ninth inning. X-rays were negative, which is significant not only for the Diamondbacks’ lineup but also for his trade value. As Arizona’s most coveted trade piece, Suárez leads MLB with 87 RBIs and has 36 home runs, but the team may be cautious with him ahead of Thursday’s deadline. His presence (or absence) in the lineup will be crucial for Arizona’s chances, as he’s been their primary run producer all season. Interestingly, Detroit has been mentioned as a potential landing spot for Suárez, adding another layer of intrigue to this matchup.

Comerica Park Factor: How the Venue Influences Today’s Game

Comerica Park has played slightly hitter-friendly this season with a 1.039 park factor for runs, though its home run factor remains pitcher-friendly at 0.928. The spacious outfield dimensions tend to turn potential home runs into doubles and triples, which benefits contact hitters. Tonight’s weather forecast calls for temperatures around 75 degrees with minimal wind, neutral conditions that shouldn’t significantly impact ball flight. The Tigers have adapted well to their home park, using the gaps effectively while their pitchers take advantage of the dimensions to limit damage. Pfaadt’s tendency to give up fly balls (43.7% fly ball rate) could be problematic in Comerica’s expansive outfield, where the Tigers’ outfielders can track down balls that might be hits in other parks.

Expert Prediction & Best Bets for Diamondbacks-Tigers Showdown

Primary Play: Detroit Tigers Moneyline (-125)

The Tigers moneyline at -125 offers solid value given the pitching matchup and recent team trends. Casey Mize has been exceptional at home with a 2.87 ERA, while Brandon Pfaadt has struggled on the road with a 5.42 ERA. Add in Arizona’s offensive woes (just 9 runs in their last 7 games) and Detroit’s strong 35-21 home record, and this price looks quite reasonable. The Tigers’ starters have thrown 21 consecutive scoreless innings, showing they’re hitting their stride, while Arizona seems to be heading in the opposite direction amid trade deadline distractions. I’d play this line up to -135.

Strong Value Play: Under 8.5 Runs (-110)

Both starters have been effective recently, and Arizona’s offense remains in a significant funk despite finally scoring an earned run yesterday. The Diamondbacks have gone under in 7 of their last 10 road games, and the Tigers’ pitching staff is performing at an elite level. With Mize’s home dominance (2.87 ERA) and Arizona’s anemic offense, runs should be at a premium. Even if Pfaadt gives up a few runs, it’s hard to see this becoming a high-scoring affair unless the Diamondbacks suddenly break out of their slump.

Worth Considering: Tigers -1.5 (+140)

If you’re looking for a higher payout, the Tigers run line at +140 is worth consideration. Detroit has won by multiple runs in 23 of their 35 home victories this season, and they’re facing a Diamondbacks team that has lost by 2+ runs in 6 of their last 9 road defeats. With Arizona’s offensive struggles and Detroit’s pitching dominance, there’s a solid chance the Tigers pull away for another comfortable win similar to Monday’s 5-1 victory.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Casey Mize Over 5.5 Strikeouts +100 ★★★★☆
Brandon Pfaadt Under 4.5 Strikeouts -115 ★★★☆☆
Spencer Torkelson To Hit a Home Run +360 ★★★★☆
Ketel Marte Over 1.5 Total Bases +120 ★★★☆☆
Riley Greene Over 0.5 RBIs +150 ★★★★☆

Final Thoughts: Tigers’ Pitching Dominance Continues

The pitching advantage in this matchup simply can’t be overlooked. Casey Mize has been masterful at home with a 2.87 ERA and the Tigers’ staff is riding a historic streak of scoreless innings by their starters. Arizona’s offense has been virtually non-existent for the past week, and they face significant uncertainty around key players like Eugenio Suárez as the trade deadline approaches. Detroit, meanwhile, has stabilized after a mid-July slump and looks to be regaining the form that made them the AL’s best team earlier this season.

When handicapping this game, I can’t ignore the massive pitching mismatch, the distinct home/road splits for both starters, and Arizona’s anemic offense. Brandon Pfaadt’s tendency to give up home runs (1.53 HR/9) makes him vulnerable in any park, and the Tigers should be able to generate enough offense to support Mize’s strong pitching. Back the Tigers at home where they’ve been one of baseball’s best teams all season.

Score Prediction: Tigers 5, Diamondbacks 2

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