Guardians vs Cubs Prediction & Best Bets | Struggling Cleveland Faces Red-Hot Imanaga in Wrigley Showdown

by | Jul 2, 2025 | mlb

Guardians vs Cubs Prediction & Best Bets | Struggling Cleveland Faces Red-Hot Imanaga in Wrigley Showdown

The struggling Cleveland Guardians (40-42) look to snap a five-game losing streak as they visit the NL Central-leading Chicago Cubs (50-35) for the second game of their series at Wrigley Field. I’ve been eyeing this pitching matchup carefully, as Shota Imanaga’s return from injury has reinvigorated the Cubs’ rotation while Cleveland’s offense has practically disappeared. With the Guardians failing to score in 43 of their last 45 innings, tonight presents a clear opportunity to capitalize on a team trending strongly in opposite directions.

Quick Picks:

  • Best Bet: Chicago Cubs Moneyline (-150) ★★★★☆
  • Top Prop: Shota Imanaga Over 5.5 Strikeouts (+110) ★★★★☆
  • Value Play: Under 7.5 Runs (-110) ★★★☆☆

Cleveland Guardians vs Chicago Cubs Betting Odds & Latest Line Movement

Market Cleveland Guardians Chicago Cubs
Moneyline +130 -150
Run Line +1.5 (-130) -1.5 (+110)
Total Over 7.5 (-110) Under 7.5 (-110)

Opening Line: Cubs -145, Total 7.5

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The overnight line movement tells an interesting story here. Despite Chicago’s dominant 5-2 win in the series opener, we’ve seen minimal movement on the moneyline from the opening -145 to -150. This suggests the market has already priced in Cleveland’s offensive struggles and Chicago’s home field advantage. More revealing is the action on the total, which has held steady at 7.5 despite Cleveland’s anemic offense. Sharp money appears to be respecting Tanner Bibee’s ability to keep games close even without run support, while also recognizing Wrigley Field’s pitcher-friendly tendencies (0.898 run factor, 25th in MLB).

Pitching Matchup: Tanner Bibee vs Shota Imanaga – Who Has the Edge?

Cleveland Guardians: Tanner Bibee (4-8, 3.90 ERA)

  • Classic case of a pitcher receiving minimal run support (2.7 runs per game)
  • Solid 82:26 K:BB ratio over 94.2 innings shows good command
  • Has allowed 3 ER or fewer in 7 of his last 8 starts
  • Struggles against left-handed hitters (.264 BAA vs LHB compared to .229 vs RHB)

Chicago Cubs: Shota Imanaga (4-2, 2.54 ERA)

  • Has been electric since returning from IL stint in mid-May
  • Impressive 37:15 K:BB ratio across 49.2 innings
  • Holding opponents to just a .209 batting average and 1.03 WHIP
  • Particularly dominant at Wrigley with a 1.88 ERA in home starts

Advantage: Chicago Cubs. While Bibee has been solid, Imanaga has been spectacular, especially at home. His deceptive delivery and four-pitch mix has continued to baffle NL hitters in his rookie campaign.

Bullpen Breakdown

The bullpen comparison further tilts this matchup toward Chicago. The Cubs’ relief corps has stabilized after early-season struggles, with Brad Keller (13 holds) providing solid setup work and Daniel Palencia (9 saves) emerging as a reliable closer. Cleveland’s bullpen remains anchored by Emmanuel Clase (18 saves) and Cade Smith (15 holds), but middle relief has been inconsistent. What’s most concerning for Cleveland is how their relievers have been taxed during this losing streak, being forced into action earlier than ideal due to offensive ineptitude putting pressure on the entire staff. The Cubs’ bullpen is better rested and has the luxury of playing with leads more frequently.

Key Betting Trends & Team Statistics That Matter

  • Cleveland has scored in only 2 of their last 45 innings – a historically bad offensive stretch
  • The Guardians are batting just .206 in June, tied for third-worst batting month in franchise history
  • Chicago is 32-14 at Wrigley Field this season, one of the best home records in MLB
  • The Cubs have won 7 of their last 9 games against teams with losing records
  • Cleveland is 2-8 in their last 10 road games against teams with winning records
  • The Under is 8-2 in the Guardians’ last 10 games overall
  • Chicago is 18-6 when Seiya Suzuki hits a home run this season

Seiya Suzuki: Cubs’ Power Surge Continues

Seiya Suzuki has been a revelation for the Cubs this season, blasting his team-leading 23rd home run in Tuesday’s series opener. What makes Suzuki particularly dangerous right now is his approach against right-handed pitching like Bibee. While Bibee has solid overall numbers, he’s allowed 14 of his 16 home runs to right-handed batters with power, precisely Suzuki’s profile. The Japanese slugger is seeing the ball extremely well right now, and with Cleveland’s pitchers forced to be perfect due to lack of run support, expect Suzuki to get at least one mistake to drive tonight.

Wrigley Field Factor: How the Venue Influences Today’s Game

Wrigley Field has played surprisingly pitcher-friendly this season with a runs factor of 0.898 (25th in MLB) and a home run factor of 0.883 (26th). This contradicts its historical reputation as a hitter’s paradise when the wind blows out. Tonight’s forecast calls for mild temperatures around 75°F with light winds (5-7 mph) blowing in from right field, further suppressing offense. This environment typically favors command pitchers like Imanaga who can limit hard contact while generating weak flyball outs. For a Cleveland team already struggling to score runs, these conditions present another significant hurdle.

Expert Prediction & Best Bets for Guardians-Cubs Showdown

Primary Play: Chicago Cubs Moneyline (-150)

This price offers solid value on the clearly superior team. Imanaga gives the Cubs a significant starting pitching advantage, and Chicago’s lineup has been clicking, especially at home. When you factor in Cleveland’s catastrophic offensive struggles (failing to score in 43 of their last 45 innings) and Chicago’s dominant 32-14 home record, laying -150 becomes an easy decision. I’d play this confidently up to -160.

Strong Value Play: Shota Imanaga Over 5.5 Strikeouts (+110)

This is my favorite prop on the board. Imanaga has exceeded this total in four of his last five starts, and Cleveland’s hitters have been pressing during their slump, leading to more aggressive at-bats and increased strikeouts. The Guardians have struck out 8+ times in seven consecutive games, and Imanaga’s deceptive delivery with multiple plus pitches makes this a prime spot for him to rack up Ks. At plus-money odds, this prop offers tremendous value.

Worth Considering: Under 7.5 Runs (-110)

With Cleveland’s offense in hibernation and Wrigley Field playing pitcher-friendly, this total has clear under potential. The Guardians have gone under in 8 of their last 10 games overall, while Imanaga has allowed 2 or fewer earned runs in 6 of his 8 starts this season. Add in light winds blowing in and two solid bullpens, and the under 7.5 becomes appealing.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Shota Imanaga Over 5.5 Strikeouts +110 ★★★★☆
Seiya Suzuki To Hit a Home Run +375 ★★★☆☆
Jose Ramirez Under 1.5 Total Bases -120 ★★★☆☆
Pete Crow-Armstrong Over 1.5 Total Bases +130 ★★★★☆
Tanner Bibee Under 5.5 Strikeouts -125 ★★★☆☆

Final Thoughts: Guardians’ Offensive Woes Continue Against Quality Cubs Starter

When a team can’t score runs, nothing else matters. The Guardians’ offense has completely disappeared, and now they face a quality starter in Shota Imanaga who has been particularly dominant at Wrigley Field. Bibee will likely keep Cleveland competitive early, but without run support, the pressure to be perfect inevitably leads to mistakes. The Cubs are playing confident baseball, getting contributions throughout their lineup, and Imanaga’s return has stabilized their rotation. I expect Chicago to continue their home dominance and extend Cleveland’s misery for at least another night.

Score Prediction: Chicago Cubs 4, Cleveland Guardians 1

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