MLB Baseball Picks

Get the latest MLB picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around starting pitching matchups, bullpen form, advanced splits, and line value. From run line and total picks to full game breakdowns, this page brings together the most actionable MLB betting content on the board.

Our MLB Betting Tips section focuses on how to bet on MLB with proven handicapping strategy and in-depth betting education, helping bettors break down matchups, understand line movement, and build a smarter, more consistent approach to MLB wagering.

MLB Picks: Giants vs. Rockies 5/16/22

MLB Picks: Giants vs. Rockies 5/16/22

The Giants got absolutely roasted by the St. Louis Cardinals last night in a game that saw slugging veteran 1B Albert Pujols come in to pitch and give up four earned runs over an inning. The Giants have now lost two in a row and head to hitter friendly ballpark Coors Field to tangle with the Colorado Rockies. Get our SFG/Col betting prediction here!

Astros vs. Red Sox Odds & Moneyline Pick

Astros vs. Red Sox Odds & Moneyline Pick

The Houston Astros are officially “still hot” after a recent loss. The team is 13-1 in their last 14 games. Unbelievably, they come in as +110 underdogs against young (and good) hurler Whitlock. Get our Hou/Bos pick here!

Yankees vs. Orioles Runline Pick 5/16/22

Yankees vs. Orioles Runline Pick 5/16/22

The Yankees and Orioles go at it at Camden Yards Monday where Luis Severino is listed as a -210 favorite. Something to consider before betting on New York is Baltimore has gone 3-4 against them in the last seven matchups. Get our NYY/Bal pick here!

Giants vs. Cardinals Odds & Picks 5/15/22

Giants vs. Cardinals Odds & Picks 5/15/22

The St. Louis Cardinals put an end to the San Francisco Giants six game win streak yesterday by shutting them out. The teams will be featured on ESPN’s Sunday Night Baseball and it should be a dandy with Carlos Rodon and Adam Wainright on the hill. Get our SF/Stl pick here!

Padres vs. Braves Odds & Moneyline Pick

Padres vs. Braves Odds & Moneyline Pick

Sunday MLB kicks off early with an 11:35AM ET game between the San Diego Padres and Atlanta Braves. Will the early start phase the west coast Pads? Get our SD/Atl pick here!

Runline Bet: Astros vs. Nationals 5/15/22

Runline Bet: Astros vs. Nationals 5/15/22

The Nats opened a can of whoop on the Astros yesterday and broke their 11-game win streak. Can they do it again Sunday? It’ll be Justin Verlander on the hill for the ‘Stros and Patrick Corbin for the Nats. Get our Hou/Wash betting prediction here!

Padres vs. Braves Odds & Pick 5/14/22

Padres vs. Braves Odds & Pick 5/14/22

The Padres put up a massive eleven-spot on the Braves yesterday, which is almost as many runs as they had scored in their previous four games. San Diego is now 5-3 over their last eight games and gaining steam. Can they keep it going Saturday against Atlanta? Get our SD/Atl betting prediction here!

MLB Betting Guide

New to betting on baseball? We've got you covered! Our comprehensive how to bet on baseball article explains all the different types of wagers offered at the sportsbooks including money lines, over/unders, run lines, parlays and more! Also get tips and strategies to increase your odds of beating the bookies!