Pirates vs Twins Prediction & Best Bets | Elite Pitching Duel Promises Low-Scoring Affair

by | Jul 11, 2025 | mlb

Pirates vs Twins Prediction & Best Bets | Elite Pitching Duel Promises Low-Scoring Affair

The Pittsburgh Pirates (42-50) head to Target Field for a weekend series against the Minnesota Twins (45-48) in what shapes up to be an elite pitching matchup between two of baseball’s most impressive arms. Paul Skenes has been nothing short of phenomenal for Pittsburgh, while Joe Ryan continues to quietly dominate for Minnesota. With both teams desperate for wins to stay relevant in the Wild Card race, this pitching showdown should produce a tactical, low-scoring battle that presents several intriguing betting opportunities.

Quick Picks:

  • Best Bet: Under 6.5 Total Runs (-110) ★★★★☆
  • Top Prop: Paul Skenes Over 7.5 Strikeouts (+100) ★★★★☆
  • Value Play: First Five Innings Under 3 (+115) ★★★☆☆

Pittsburgh Pirates vs Minnesota Twins Betting Odds & Latest Line Movement

Market Pittsburgh Pirates Minnesota Twins
Moneyline +125 -145
Run Line +1.5 (-150) -1.5 (+130)
Total Over 6.5 (-110) Under 6.5 (-110)

Opening Line: Twins -135, Total 7

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

Since opening, we’ve seen the total drop from 7 to 6.5, indicating sharp money has come in on the under despite this relatively low number. Professional bettors clearly respect the pitching matchup between Skenes and Ryan, two of the most dominant arms in baseball this season. The moneyline has also seen a slight move toward Minnesota from -135 to -145, suggesting some respected money believes the home field advantage will be significant in what projects to be a tight, low-scoring affair. The run line has remained stable, with sharps likely viewing this as a one-run game either way.

Pitching Matchup: Paul Skenes vs Joe Ryan – Who Has the Edge?

Pittsburgh Pirates: Paul Skenes (4-7, 1.94 ERA)

  • The 2024 #1 overall pick has been historically good, posting a sub-2.00 ERA through his first 116 MLB innings
  • Elite K/BB ratio of 125:30 demonstrates his exceptional command and dominance
  • Microscopic 0.92 WHIP ranks among the best in baseball
  • Has been the victim of poor run support, explaining his losing record despite elite performance

Minnesota Twins: Joe Ryan (8-4, 2.76 ERA)

  • Putting together a career year with a 2.76 ERA across 104.1 innings
  • Outstanding 116:21 K/BB ratio shows elite command and swing-and-miss stuff
  • 0.89 WHIP is actually better than Skenes’, indicating how dominant he’s been
  • Has been nearly unhittable at Target Field with a 2.10 ERA in home starts this season

Advantage: Slight edge to Skenes based on pure stuff, but this is essentially a push. Both pitchers are performing at an elite level and capable of completely shutting down opposing lineups.

Bullpen Breakdown

Minnesota holds a clear advantage in the bullpen department. The Twins’ relief corps is anchored by closer Jhoan Duran (1.52 ERA, 14 saves) and setup man Griffin Jax, who has been one of baseball’s best relievers with a 4.12 ERA but exceptional 1.92 FIP and 14.6 K/9. The Twins’ bullpen ranks 7th in MLB with a 3.61 ERA. Pittsburgh’s bullpen has been inconsistent, posting a 4.24 ERA (20th in MLB), though closer David Bednar (2.70 ERA, 12 saves) provides stability in the ninth. If this game stays close into the late innings, Minnesota’s deeper and more effective bullpen gives them a significant edge.

Key Betting Trends & Team Statistics That Matter

  • Paul Skenes has allowed 2 or fewer runs in 14 of his 16 starts this season
  • Joe Ryan has struck out 7+ batters in 11 of his 15 starts
  • The Pirates are just 4-12 in Skenes’ starts despite his 1.94 ERA due to terrible run support (2.7 runs per game)
  • Minnesota is 10-5 in Joe Ryan’s starts this season
  • Pittsburgh ranks 29th in MLB in runs scored (3.39 per game) and 28th in OPS (.642)
  • The Twins rank 13th in runs scored (4.16 per game) but have struggled lately, scoring 3 or fewer runs in 6 of their last 9 games
  • The under is 11-5 in Paul Skenes’ starts this season
  • The under is 9-6 in Joe Ryan’s starts in 2025

Byron Buxton Factor: The Twins’ Dynamic Centerfielder Returns

After missing Thursday’s game with a bruised hand, Byron Buxton is expected to return to the Twins’ lineup tonight. Buxton has been having a resurgent season, slashing .282/.364/.547 with 20 home runs and 16 stolen bases. His presence transforms Minnesota’s lineup, providing both power and speed. However, he’ll face a tough test against Skenes, who has held right-handed hitters to a measly .185 batting average this season. How Buxton performs against the Pirates’ phenom could be the decisive factor in determining the outcome of this matchup.

Target Field Factor: How the Venue Influences Today’s Game

Target Field ranks almost exactly neutral for run scoring with a 1.001 factor (12th in MLB) and a 1.003 factor for home runs. The weather forecast calls for temperatures in the mid-70s with minimal wind, creating perfect conditions for pitchers. The dimensions aren’t particularly favorable to either lefties or righties, making this a fair playing field for both teams. Given the elite pitching matchup and the neutral park factors, environmental conditions should have minimal impact on the game, allowing the skill of these two outstanding pitchers to determine the outcome.

Expert Prediction & Best Bets for Pirates-Twins Showdown

Primary Play: Under 6.5 Total Runs (-110)

This total is simply too high given the pitching matchup we’re looking at. Paul Skenes has been virtually unhittable all season, while Joe Ryan has been equally dominant, especially at home. Pittsburgh’s offense ranks among the worst in baseball, scoring just 3.39 runs per game, and they’ll be facing an elite starter backed by one of baseball’s best bullpens. Even if one of these pitchers has an off night (unlikely), it would be hard to envision both teams combining for 7+ runs. I’d play this under down to 6 runs.

Strong Value Play: Paul Skenes Over 7.5 Strikeouts (+100)

The Twins strike out at a league-average rate (8.28 K/game), while Skenes has been racking up punchouts all season with his 100+ mph fastball and devastating breaking pitches. He’s recorded 8+ strikeouts in 9 of his 16 starts this season, and Minnesota’s aggressive approach should play right into his hands. At even money, there’s significant value in backing the rookie phenom to continue his strikeout dominance.

Worth Considering: First Five Innings Under 3 (+115)

If you like the full game under, the first five innings under 3 offers even more value. Both Skenes and Ryan should dominate early, and I wouldn’t be surprised to see a scoreless tie through 4-5 innings. At plus money, this offers a great opportunity to capitalize on what should be a pitcher’s duel from the outset.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Paul Skenes Over 7.5 Strikeouts +100 ★★★★☆
Joe Ryan Over 6.5 Strikeouts -120 ★★★★☆
Byron Buxton Under 1.5 Total Bases -130 ★★★☆☆
Oneil Cruz To Record a Hit -165 ★★★☆☆
No Run First Inning Yes -150 ★★★★☆

Final Thoughts: Expect a Classic Pitcher’s Duel in Minneapolis

Tonight’s matchup features two of the most dominant pitchers in baseball, and I’m expecting runs to be at an absolute premium. Paul Skenes has been everything the Pirates hoped for when they drafted him first overall, while Joe Ryan has quietly established himself as one of the most effective starters in the American League. The betting value clearly lies with the under in what should be a classic pitcher’s duel. Minnesota’s superior offense and bullpen give them a slight edge to win outright, but the total is the clearest play on the board.

Score Prediction: Minnesota Twins 2, Pittsburgh Pirates 1

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