MLB Picks: Rays vs Reds Best Bets for July 25

by | Jul 25, 2025 | mlb

Rays vs Reds Prediction & Best Bets | Pitching Duel in Great American Bandbox

The Tampa Bay Rays (53-50) head to Cincinnati to face the Reds (53-50) in what promises to be an intriguing interleague matchup at Great American Ball Park. With both teams sporting identical records and fighting for wild card positions in their respective leagues, this series opener features a compelling pitching matchup between Zack Littell and Nick Martinez. I’m particularly interested in how Littell’s efficiency will play against Cincinnati’s aggressive offense in one of baseball’s most homer-friendly venues.

Quick Picks:

  • Best Bet: Tampa Bay Rays Moneyline (-112) ★★★★☆
  • Top Prop: Zack Littell Over 5.5 Strikeouts (+105) ★★★★☆
  • Value Play: Under 9.5 Runs (-115) ★★★☆☆

Tampa Bay vs Cincinnati Betting Odds & Latest Line Movement

Market Tampa Bay Rays Cincinnati Reds
Moneyline -112 -104
Run Line -1.5 (+138) +1.5 (-166)
Total Over 9.5 (-105) Under 9.5 (-115)

Opening Line: Rays -115, Total 9

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The line movement in this game has been minimal, showing a slight drift toward Cincinnati despite Tampa Bay opening as a slight road favorite. This subtle movement indicates professional money might be showing some respect for the Reds at home, though not with enough conviction to dramatically shift the line.

What’s more interesting is the total holding firm at 9.5 despite Great American Ball Park’s reputation as a launching pad (1.384 HR factor, highest in MLB). Sharp bettors appear to be respecting the pitching matchup more than the venue factors, which aligns with my analysis of Littell’s recent performance and efficiency.

Pitching Matchup: Zack Littell vs Nick Martinez – Who Has the Edge?

Tampa Bay Rays: Zack Littell (8-7, 3.53 ERA)

  • Outstanding control with just 17 walks in 122.1 innings pitched
  • Impressively efficient with a 1.09 WHIP, limiting traffic on the basepaths
  • Averaging 6.1 innings per start, providing consistent length for the Rays
  • Excellent command of his slider and splitter, generating weak contact

Cincinnati Reds: Nick Martinez (8-9, 4.73 ERA)

  • Struggling with consistency, as evidenced by his elevated 4.73 ERA
  • Allowing too much hard contact with a 1.22 WHIP and elevated HR rate
  • Pitched better at home (4.21 ERA) than on the road (5.13 ERA)
  • Has allowed 18 home runs this season, a concerning stat heading into this matchup

Advantage: Tampa Bay. Littell’s superior command and efficiency give the Rays a significant edge in this matchup. While Martinez has shown flashes, his tendency to surrender home runs is particularly troublesome in a park that amplifies power.

Bullpen Breakdown

The Rays’ bullpen has been a rollercoaster this season, with recent struggles before the All-Star break followed by improved performance since. Pete Fairbanks leads the team with 17 saves but has had some shaky outings. The recent improvement from Edwin Uceta (5.2 scoreless innings with 11 strikeouts over his last three appearances) provides a crucial bridge to Fairbanks.

Cincinnati counters with a solid bullpen anchored by Emilio Pagán (21 saves) and setup man Tony Santillan (20 holds). The Reds’ relief corps has been more consistent overall, though they’ve been worked heavily in recent games.

Given Tampa Bay’s starting pitching advantage with Littell likely to work deeper into the game, I expect less pressure on the Rays’ bullpen tonight, neutralizing Cincinnati’s potential advantage in this area.

Key Betting Trends & Team Statistics That Matter

  • Tampa Bay is 45-54 ATS this season, while Cincinnati has performed better at 51-46 ATS
  • The Rays are 30-22 as favorites this season, winning at a 57.7% clip
  • Cincinnati has been surprisingly good as an underdog at 28-26 (51.9% win rate)
  • Both teams have similar records against the over/under (TB: 40-59, CIN: 42-52-3)
  • Cincinnati’s Great American Ball Park ranks 5th in runs factor (1.093) but 1st in home run factor (1.384)
  • Tampa Bay is 8-12 ATS in Littell’s starts, while Cincinnati is 9-11 ATS in Martinez’s starts

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Chandler Simpson: MLB’s Fastest Player Takes On Elly De La Cruz

Tonight features an exciting subplot as recently MLB players voted Tampa Bay’s Chandler Simpson as baseball’s fastest player, edging out Cincinnati’s Elly De La Cruz. Interestingly, Simpson himself voted for De La Cruz, calling him “relentless” with the mindset of “me versus you, I’ve got myself over anybody.”

This speed matchup adds intrigue to tonight’s game, as both players are among MLB’s stolen base leaders (Simpson with 31, De La Cruz with 27). In a close game, either player could create a game-changing moment on the basepaths.

The speed element also factors into my handicapping approach, as Tampa Bay may be able to exploit Martinez’s average delivery time to home plate (1.3 seconds), potentially creating extra scoring opportunities through their running game.

Great American Ball Park Factor: How the Venue Influences Today’s Game

Great American Ball Park is famously hitter-friendly, particularly for power hitters. The park ranks 5th in MLB with a 1.093 runs factor but leads all ballparks with a staggering 1.384 home run factor.

This venue effect would typically push me toward the over, but Littell’s exceptional command (just 1.25 BB/9) minimizes free baserunners, which is crucial for limiting damage in homer-friendly parks. His ability to keep the ball on the ground (44.2% ground ball rate) further neutralizes the park’s home run tendencies.

The weather forecast calls for temperatures in the low 80s with minimal wind, providing neutral conditions that won’t further enhance the park’s hitter-friendly nature.

Expert Prediction & Best Bets for Rays-Reds Showdown

Primary Play: Tampa Bay Rays Moneyline (-112)

I’m backing the Rays behind Zack Littell’s superior command and efficiency. His 1.09 WHIP and excellent 4.88 K/BB ratio demonstrate his ability to limit traffic on the basepaths, which is critical in a hitter-friendly park like Great American. While Martinez has pitched better at home, his elevated HR rate is concerning against a Rays lineup that can do damage when pitchers miss in the zone. At nearly even money, the Rays offer solid value in a game where the pitching matchup tilts clearly in their favor.

Strong Value Play: Zack Littell Over 5.5 Strikeouts (+105)

Littell isn’t known as a dominant strikeout pitcher, but this matchup sets up well for him to exceed his season average. The Reds rank 8th in MLB in strikeouts per game (8.55), and Littell’s command should allow him to work deep enough to accumulate the necessary punchouts. At plus money, this prop offers excellent value considering Cincinnati’s swing-and-miss tendencies and Littell’s efficiency that should get him into the 6th or 7th inning.

Worth Considering: Under 9.5 Runs (-115)

Despite the venue’s reputation for high scoring, I’m leaning under due to Littell’s ability to limit walks and home runs. The Rays’ starter has allowed just 17 walks all season, and his command should neutralize some of Cincinnati’s offensive potential. While Martinez is more vulnerable, Tampa Bay’s offense ranks middle-of-the-pack in runs scored. The total of 9.5 feels a touch high for a game featuring one highly efficient starter.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Zack Littell Over 5.5 Strikeouts +105 ★★★★☆
Junior Caminero To Hit a Home Run +380 ★★★★☆
Yandy Díaz Over 1.5 Total Bases +125 ★★★☆☆
Elly De La Cruz To Steal a Base +150 ★★★☆☆
Nick Martinez Under 4.5 Strikeouts -120 ★★★☆☆

Final Thoughts: Rays’ Pitching Edge Trumps Reds’ Home Field Advantage

This matchup features two teams with identical records fighting for wild card positioning in their respective leagues. While the venue would typically favor Cincinnati’s power-hitting lineup, Littell’s command and efficiency should be the difference-maker tonight. His ability to limit walks (just 1.25 BB/9) is particularly valuable in a park that punishes free passes with home runs.

Martinez’s vulnerability to the long ball (1.4 HR/9) creates a significant concern against a Tampa Bay lineup featuring power threats like Junior Caminero, who enters on a seven-game hitting streak with four homers in his last ten games.

Score Prediction: Tampa Bay Rays 5, Cincinnati Reds 3

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