Detroit Tigers vs Pittsburgh Pirates Prediction & Betting Pick – July 21

by | Jul 21, 2025 | mlb

Tigers vs Pirates Prediction & Best Bets | Phenom Skenes Aims to Cool Red-Hot Detroit

The MLB’s best team by record travels to Pittsburgh as the Detroit Tigers (60-40) visit the struggling Pirates (39-61) at PNC Park. This interleague matchup features a fascinating pitching duel between veteran Jack Flaherty and rookie sensation Paul Skenes. Despite Pittsburgh’s recent woes, including being swept by the White Sox over the weekend, Skenes gives them legitimate hope in any game he starts. The Tigers, meanwhile, snapped a six-game losing streak with Sunday’s win over Texas and look to build momentum as baseball’s first 60-win team.

Quick Picks:

  • Best Bet: Pirates Moneyline (-122) ★★★★☆
  • Top Prop: Paul Skenes Over 7.5 Strikeouts (+115) ★★★★☆
  • Value Play: Under 7 Total Runs (-110) ★★★☆☆

Detroit Tigers vs Pittsburgh Pirates Betting Odds & Latest Line Movement

Market Detroit Tigers Pittsburgh Pirates
Moneyline +102 -122
Run Line +1.5 (-185) -1.5 (+155)
Total Over 7 (-110) Under 7 (-110)

Opening Line: Pirates -115, Total 7

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The line movement in this game tells an interesting story. Despite the Tigers having baseball’s best record and the Pirates coming off a sweep, sharp money has pushed Pittsburgh from -115 to -122. This movement signals professional respect for Skenes regardless of team form. The total has held steady at 7, reflecting the expected pitching duel between Flaherty’s veteran savvy and Skenes’ elite stuff. When sharps are willing to back a struggling team like Pittsburgh against MLB’s best record, I pay close attention.

Pitching Matchup: Jack Flaherty vs Paul Skenes – Who Has the Edge?

Detroit Tigers: Jack Flaherty (5-9, 4.65 ERA)

  • Has struggled with consistency this season, posting a 1.24 WHIP across 100.2 innings
  • Elite strikeout numbers with 124 Ks (11.1 K/9), showing his stuff remains effective
  • Control issues persist with 40 walks (3.6 BB/9)
  • Tigers are just 6-13 in his 19 starts this season despite team’s overall success
  • Last outing: 5.0 IP, 2 ER, 4 H, 2 BB, 7 K against Cleveland

Pittsburgh Pirates: Paul Skenes (4-8, 2.01 ERA)

  • NL All-Star Game starter despite rookie status, showing his immediate elite impact
  • Dominant 0.93 WHIP and 131 strikeouts over 121 innings (9.7 K/9)
  • Excellent command with just 30 walks (2.2 BB/9)
  • Has allowed 2 earned runs or fewer in 17 of 20 starts
  • Pirates are 9-11 in his starts despite his excellence, highlighting team’s offensive struggles
  • Last outing: 5.0 IP, 2 ER, 5 H, 0 BB, 6 K against Milwaukee

Advantage: Significant edge to Pittsburgh. While Flaherty can still miss bats at an elite level, Skenes has been one of MLB’s most dominant pitchers regardless of experience. His combination of velocity, command, and secondary offerings gives Pittsburgh a clear advantage in this pitching matchup.

Bullpen Breakdown

Detroit’s bullpen has been a glaring weakness during their recent skid, with inconsistency plaguing what was previously a strength. Will Vest (16 saves) has been reliable, but the middle relief corps has struggled. Tyler Holton and Brenan Hanifee have been serviceable setup men with 10 and 9 holds respectively, but the Tigers have been actively seeking bullpen reinforcements on the trade market. Pittsburgh’s relief corps features All-Star closer David Bednar (13 saves) and reliable setup options in Dennis Santana and Caleb Ferguson. While neither bullpen is elite, Pittsburgh has shown more stability in high-leverage situations over the past two weeks, giving them a slight edge if this game goes deep into the late innings.

Key Betting Trends & Team Statistics That Matter

  • Detroit became the first MLB team to reach 60 wins with Sunday’s victory over Texas
  • The Tigers have gone 4-6 in their last 10 games, including a six-game losing streak
  • Pittsburgh has lost 10 of their last 11 games and was just swept by the White Sox
  • The Pirates were outscored 27-7 in their three-game sweep at the hands of Chicago
  • Skenes has allowed 2 or fewer earned runs in 85% of his starts this season (17 of 20)
  • Detroit ranks 9th in MLB with 125 home runs but has struggled with offensive consistency recently
  • PNC Park ranks as slightly hitter-friendly for runs (1.054 factor) but suppresses home runs (0.893)
  • The Under is 4-1 in the Tigers’ last 5 road games

Paul Skenes: Rookie Sensation Looking to Silence MLB’s Best Team

Paul Skenes has been nothing short of phenomenal in his rookie campaign, already establishing himself as one of baseball’s premier starting pitchers. Despite an underwhelming win-loss record (4-8) caused by Pittsburgh’s anemic offense, his 2.01 ERA ranks among MLB’s best. The former #1 overall pick’s triple-digit fastball paired with a devastating splitter has generated a 30.4% strikeout rate while limiting opponents to a .187 batting average. Against a Tigers lineup that struggled during their recent six-game skid (averaging just 2.5 runs per game), Skenes has a prime opportunity to demonstrate why he was the NL’s All-Star Game starter and is already in the Cy Young conversation despite his rookie status.

PNC Park Factor: How the Venue Influences Today’s Game

PNC Park offers a slightly favorable environment for run-scoring with a 1.054 park factor, but its expansive left field suppresses home runs (0.893 factor). This configuration plays well for pitchers like Skenes who can generate weak contact and keep the ball in the park. The warm July weather (projected 84° at first pitch) could help carry a few deep flies, but evening conditions in Pittsburgh typically favor pitchers as the game progresses. The picturesque backdrop can also be disorienting for visiting hitters unfamiliar with the sight lines. For Detroit, a team that relies significantly on the long ball, PNC Park’s homer-suppressing tendencies could prove problematic, especially against a pitcher of Skenes’ caliber who already limits hard contact.

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Expert Prediction & Best Bets for Tigers-Pirates Showdown

Primary Play: Pittsburgh Pirates Moneyline (-122)

I’m betting against baseball’s best team record-wise here, but with good reason. When you have a generational talent like Paul Skenes on the mound, team records become secondary. The rookie phenom has been absolutely dominant with his 2.01 ERA and 0.93 WHIP, giving him a substantial edge over the inconsistent Flaherty. Detroit may have the superior overall team, but they’ve struggled recently with a 4-6 record in their last 10 games. When I can get the better pitcher at a reasonable price, I’ll take that edge regardless of overall team performance. The Pirates’ moneyline at -122 offers solid value that I’d play up to -135.

Strong Value Play: Paul Skenes Over 7.5 Strikeouts (+115)

Skenes has elite strikeout stuff, evidenced by his 131 Ks in 121 innings. While his season average (9.7 K/9) puts him slightly below this total, he’s cleared 8+ strikeouts in 7 of his 20 starts this season. The Tigers have been more strikeout-prone during their recent struggles, and Skenes has the kind of overpowering arsenal that can exploit an offense pressing to break out of a slump. At plus money, this prop offers tremendous value on one of baseball’s most electric arms in a favorable matchup.

Worth Considering: Under 7 Total Runs (-110)

With Skenes on the mound and the Tigers’ offense still trying to rediscover its consistent form, this has all the makings of a low-scoring affair. Detroit’s lineup has shown vulnerability against elite pitching, and Skenes certainly qualifies. While Flaherty has been inconsistent, he still possesses swing-and-miss stuff that can quiet Pittsburgh’s already struggling offense. Given both pitchers’ strikeout potential and the modest total of 7, the under looks appealing.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Paul Skenes Over 7.5 Strikeouts +115 ★★★★☆
Jack Flaherty Over 5.5 Strikeouts -120 ★★★☆☆
Riley Greene Under 1.5 Total Bases -135 ★★★★☆
Oneil Cruz To Record an RBI +195 ★★☆☆☆

Final Thoughts: Betting Against MLB’s Best Record When Talent Dictates

This matchup perfectly illustrates why we bet on individual games rather than season-long records. While Detroit has been outstanding overall, securing MLB’s first 60 wins, they face a significant disadvantage on the mound tonight. Paul Skenes represents the rare talent who can singlehandedly level the playing field against superior competition. His dominance (2.01 ERA, 0.93 WHIP) gives Pittsburgh legitimate win equity regardless of their recent struggles. When a pitcher of this caliber is available at a reasonable price against a team that’s shown recent vulnerability, I’m happy to back the underperforming team with the superior starter. The Pirates’ moneyline offers solid value, and I expect Skenes to deliver a gem that validates the market’s movement in Pittsburgh’s favor.

Score Prediction: Pirates 3, Tigers 1

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