Cardinals vs. Padres Moneyline Bet 9/21/22

by | Last updated Sep 21, 2022 | mlb

St. Louis Cardinals vs San Diego Padres

Date: Wednesday September 21st, 09:40 ET

Location: Petco Park

TV: Bally Sports Midwest

Money Line: Cardinals -105 / Padres -115 (BAS – Bet on MLB games at reduced odds! Why pay more?)

Total Line: 7.5


St. Louis: Miles Mikolas (11-12, 3.46)
San Diego: Blake Snell (7-9, 3.93)


St. Louis Cardinals: 87-62-0 SU / OU 70-74-5 / Run Line W/L 82-67-0
San Diego Padres: 82-66-0 SU / OU 68-75-5 / Run Line W/L 66-82-0

The San Diego Padres host the St. Louis Cardinals on Wednesday September 21st at Petco Park. The first pitch in this matchup is scheduled for 09:40 ET. The MLB Odds Board places San Diego as the favorite (-115), with an OU line set at 7.5.

Recent Form

The Cardinals will look to bounce back from a tough loss to the San Diego by the score of 5-0. On their way to giving up 5 runs, the Cardinals staff allowed 10 hits. Offensively, they finished with just 0 runs on 5 hits. Cardinals suffered the loss, despite being favored at -105.0. So far, the team has been the favorite in 100 of their games, winning at a rate of 68.0%. Together, the Cardinals and San Diego stayed below the over-under line set at 8.0 runs. This outcome pushed St. Louis’s over-under record further below .500 at 70-74-5.

The Cardinals are looking to continue adding wins, as they are 3-2 over their last 5 games. However, even with an above .500 record (last 5) their run differential sits at just -2 (last 5). St. Louis has put together this record, despite averaging just 2.4 runs per game, compared to their season average of 4.79. So far, St. Louis has won over half of their 46 series played, going 25-11-10.

The San Diego Padres are coming off a big win over the Cardinals by a score of 5-0. For the game, the pitching staff held the Cardinals to 0 runs on 5 hits. In the victory, the Padres came up with 10 hits and 5 runs. San Diego picked up the win while being favored at -115.0. So far, the team has won 57.9% of the games in which they were favored. With this result, the Padres and Cardinals combined to fall below the over-under line of 8.0 runs. Now, San Diego had an over-under record of 68-75-5.

In their last 5 games, the Padres have put together a record of 4-1. Their recent success is backed by an average scoring margin of +17 (last 5). San Diego has benefited from strong pitching, as their offense has slipped in their last 5 games, averaging just 5.0 runs per game. Their overall average sits at 4.38. On the season, San Diego has won more than half of their series, going 24-16-7.

Pitching Matchup

Miles Mikolas gets the start for the Cardinals, with an overall record of 11-12. So far, Mikolas has put together an ERA of 3.46. In his appearances leading up to today, he has lasted an average of 6.24 innings. Mikolas comes into the game with a batting average allowed of 0.23. Opponents are hitting for power against Mikolas, as his HR/9 figure sits at 1.15. Per game, Miles Mikolas is averaging 4.6, on a strikeout percentage of 18.0%. In his previous outings, walks have been an issue, as Mikolas is averaging 1.73 free passes per outing.

The San Diego Padres will send Blake Snell to the mound with an overall record of 7-9. So far, Snell has put together an ERA of 3.93. In his appearances leading up to today, he has lasted an average of 5.24 innings. Snell comes into the game with a batting average allowed of 0.236. Opposing batters are hitting for power at a below-average rate against Snell, as he is allowing just 0.82 per 9 innings. In terms of strikeouts, Blake Snell has a strong K% of 31.0%, including a per-game average of 6.95. For the season, he has struggled with command averaging 3.68 walks per outing.

St. Louis vs San Diego History

Today’s matchup between the St. Louis Cardinals and San Diego Padres will be their 5th meeting of the season. St. Louis has the lead in the series at 3-1. Through 4 games, the series’ over-under record is 0-3, with the average run total sitting at 10.5 runs per game. In these matchups, the average scoring differential sits at 3.0 runs. Last year, the team’s split the season series at 3-3. In these 6 meetings, the two teams combined for an over-under record of 5-1. Last year, the Cardinals and Padres averaged 10.5 runs per game. On average, the winning team won by a margin of 3.5 runs per contest.

Betting Trends

  • St. Louis is 5-0 SU in its last 5 games when playing San Diego
  • The total has gone UNDER in 5 of St. Louis’s last 6 games
  • San Diego is 5-0 SU in its last 5 games when playing at home against St. Louis
  • The total has gone OVER in 5 of San Diego’s last 5 games at home

St. Louis Cardinals at San Diego Padres Prediction

Leading into Wednesday’s National League matchup between St. Louis and San Diego, the Padres have a slight edge on the moneyline. Look for the Cardinals’ offensive struggles to continue against Blake Snell, who aside from a tough outing vs the Dodgers has been excellent of late. I recommend taking the Padres on the moneyline.

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