Baltimore Orioles (32-31) +150, 10 at Boston Red Sox (40-27), 7:05 pm Eastern Wednesdayby Zman of Predictem.com After winning the opener of a three-game series at Fenway Park Tuesday night, the Baltimore Orioles will look to creep a little closer to the lead in the AL...
MLB Baseball Picks
Get the latest MLB picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around starting pitching matchups, bullpen form, advanced splits, and line value. From run line and total picks to full game breakdowns, this page brings together the most actionable MLB betting content on the board.
Our MLB Betting Tips section focuses on how to bet on MLB with proven handicapping strategy and in-depth betting education, helping bettors break down matchups, understand line movement, and build a smarter, more consistent approach to MLB wagering.
Chicago White Sox vs. Detroit Tigers Preview and Pick
Chicago White Sox (37-26) PK, 9 1/2 at Detroit Tigers (26-37), 7 pm Eastern Tuesdayby Zman of Predictem.com The surprise leaders of the American League's Central Division visit the pre-season Central favorites when the Chicago White Sox hit the Motor City for the...
New York Yankees vs. Oakland A’s Preview and Pick – 28089
New York Yankees (32-32) -130, 8 at Oakland A's (34-29), 10 pm Eastern Tuesdayby Zman of Predictem.com The New York Yankees, in search of a push that will get them closer to contention in the AL East, embark on a six-game road trip, beginning with three games in...
Cleveland Indians vs. Detroit Tigers Preview and Pick – Lee vs. Willis
Cleveland Indians (28-35) PK, 9 at Detroit Tigers (26-36), 7 pm Eastern Monday, ESPNby Zman of Predictem.com Supposed AL Central contenders collide when the Cleveland Indians and Detroit Tigers meet for the finale of a four-game series at Comerica Park Monday night....
Tampa Bay Rays vs. Los Angeles Angels – Jackson vs. Saunders
Tampa Bay Rays (37-26) +135, 8 at Los Angeles Angels (39-25), 10 pm Eastern Mondayby Zman of Predictem.com The best of the AL West meets the most pleasant surprise in baseball so far this season when the Los Angeles Angels play host to the Tampa Bay Rays for the...
Cincinnati Reds vs. Florida Marlins Preview and Pick – Volquez vs. Hendrickson
Cincinnati Reds (30-33) Edinson Volquez -140, 9 O/U at Florida Marlins (33-28) Mark Hendrickson +120, 9 O/U, Dolphin Stadium, 7:05 PM EST, Mondayby Badger of Predictem.com The Cincinnati Reds have to like their chances in the finale of their four-game set with the...
Los Angeles Angels vs. Oakland A’s Preview and Pick
Los Angeles Angels (37-24) -115, 7 at Oakland A's (33-27), 10 pm Eastern Fridayby Zman of Predictem.com The two best teams in the American League West so far this season clash when the Los Angeles Angels visit NoCal to take on the Oakland A's in the opener of a...
Minnesota Twins vs. Chicago White Sox Preview and Pick – Blackburn vs. Vazquez
Minnesota Twins (31-29) +155, 8 at Chicago White Sox (33-26), 8:10 pm Eastern Fridayby Zman of Predictem.com The AL Central gets a bit of early-season pennant fever when the Minnesota Twins and Chicago White Sox, the top two teams in the division, commence a four-game...
Cleveland Indians vs. Texas Rangers Preview and Pick – Lee vs. Ponson
Cleveland Indians (26-32) -140, 10 at Texas Rangers (30-30), 8 pm Eastern Wednesdayby Zman of Predictem.com The Texas Rangers look to continue their recent good play when they host the Cleveland Indians for game 3 of a four-game set Wednesday night at The Ballpark in...
Kansas City Royals vs. Chicago White Sox Preview and Pick – (Gil Meche vs. Jose Contreras)
Kansas City Royals (23-36) +150, 8 at Chicago White Sox (32-26), 8:10 pm Eastern Thursdayby Zman of Predictem.com The first-place team in the AL Central looks to complete a three-game sweep of the last-place team in the Central when the Chicago White Sox host the...
MLB Baseball Picks
Rockies vs. Cubs Prediction: Assad’s 5.63 K/9 and a Price That Doesn’t Add Up- Pirates vs. Athletics Prediction: Civale’s IL Status Changes the Math
- Orioles vs. Mariners Pick: Bradish’s 4.79 BB/9 Puts Pressure on the Total
- Giants vs. Braves Prediction: Truist Park’s Neutral Factor Exposes a Generous Total
- White Sox vs. Yankees Prediction: Rodon’s Arsenal Meets a Gutted Run Environment
- Rockies vs. Cubs Prediction: Assad’s 5.63 K/9 and a Price That Doesn’t Add Up
- Pirates vs. Athletics Prediction: Civale’s IL Status Changes the Math
- Orioles vs. Mariners Pick: Bradish’s 4.79 BB/9 Puts Pressure on the Total
- Giants vs. Braves Prediction: Truist Park’s Neutral Factor Exposes a Generous Total
- White Sox vs. Yankees Prediction: Rodon’s Arsenal Meets a Gutted Run Environment
MLB Betting Guide
New to betting on baseball? We've got you covered! Our comprehensive how to bet on baseball article explains all the different types of wagers offered at the sportsbooks including money lines, over/unders, run lines, parlays and more! Also get tips and strategies to increase your odds of beating the bookies!