St. Louis Cardinals vs. San Francisco Giants Moneyline Pick

St. Louis Cardinals vs. San Francisco Giants
Date: Thursday, April 27th, 3:45 ET
Location: Oracle Park
TV: MLBN
Money Line: Cardinals +128/Giants -151
Total Line: 8.5

Betting Preview

Here’s our betting preview for the upcoming MLB clash between the San Francisco Giants and the Cardinals on Thursday, April 27th at Oracle Park. We provide you with a comprehensive analysis, odds, and predictions to help with your handicapping decision or tail our expert based on the projected lineups and listed starting pitchers.

Betting Odds

Cardinals vs. Giants Projected Lineup

	Batting Order	Position
Brendan Donovan	1	2B
Alec Burleson	2	RF
Paul Goldschmidt	3	1B
Nolan Arenado	4	3B
Willson Contreras	5	C
Nolan Gorman	6	2B
Lars Nootbaar	7	RF
Dylan Carlson	8	CF
Tommy Edman	9	SS
Miles Mikolas	–	SP




	Batting Order	Position
LaMonte Wade Jr.	1	1B
Thairo Estrada	2	2B
Michael Conforto	3	LF
Mike Yastrzemski	4	CF
Joc Pederson	5	LF
J.D. Davis	6	3B
Brandon Crawford	7	SS
Blake Sabol	8	C
Joey Bart	9	C
Logan Webb	–	SP




Straight Up/Over-Under/ Runline Record

St. Louis Cardinals: 9-16 SU / OU 12-13 / Runline 11-14
San Francisco Giants: 11-13 SU / OU 12-10 / Runline 11-13

If the Cardinals are going to climb out of last place in the NL Central, they will need to turn things around with a win over the Giants. Heading into the game, the Cardinals have lost three straight games and stand with an overall record of 9-16. On the road, the Cardinals are 4-8 and 5-8 at home. The team’s overall series record is 2-4.

• The Cardinals have covered the runline in 44.0% of their games and have an average run margin of -0.4
• The Cardinals have been favored in 64.0% of their games and have runline records of 5-8 and 6-6 at home and on the road, respectively
• So far, the Cardinals have an over/under record of just 12-13.

On a record of 11-13, the Giants are 4th in the NL West. Currently, they are two games out of the division lead. Against the Cardinals, they will be seeking their 6th straight win. On the road, they have a record of 4-7 while going 7-6 at home. San Francisco’s overall series record is 1-5.

• The Giants have covered the runline in 45.8% of their games and have an average run margin of -0.2
• The Giants have been favored in 37.5% of their games and have runline records of 6-7 and 5-6 at home and on the road, respectively
• The over has hit in 55% of the Giants’ 24 games at 12-10.

Pitching Matchup




Starter Miles Mikolas comes in with an overall record of 0-1 for the Cardinals. Having made five appearances, his ERA is 7.46 and he has a K/9 figure of 0.9. Additionally, he has a FIP of 5.53 and an OBP of .395.

Miles Mikolas’ most recent outing saw him face the Mariners, where he allowed three runs and five hits in 5 1/3 innings of work. the Cardinals ended up losing the game by a score of 5-4.




With an overall record of 1-4, the Giants will give Logan Webb the start. His ERA stands at 4.40, with a K/9 figure of 1.2 after making five appearances. Additionally, he has a FIP of 4.01 and an OBP of .295.

The last time Logan Webb took to the mound, he secured a quality start and a win for his team, who won by a final score of 7-4 against the Mets. Webb gave up two runs and five hits across seven innings.

Cardinals vs. Giants Offense Outlook

At 4.4 runs per game, St. Louis is ranked 16th in the league in terms of runs scored this season. In terms of home runs, they have gone deep 30 times so far. The team’s batting average of .267 places them 4th in the league. When playing on the road, their batting average is ranked 13th compared to 1st at home.

St. Louis Cardinals Top Hitters vs. Righties




St. Louis Cardinals Top Hitters: Last Five Games




The Giants have played 24 games and are currently ranked 16th in the league, averaging 4.6 runs per game. San Francisco ranks 4th in home runs, (38) and have a collective batting average of .243, including .230 on the road and .240 at home.

San Francisco Giants Top Bats




San Francisco Giants Top Hitters: Last Five Games




Free MLB Pick

The Cardinals have played very poorly on their road trip. going 1-5. Overall, they’re 2-7 in their last nine games. They’ll send Mikolas to the mound who has been equally bad with a 7.46 ERA and 1.89 WHIP. That’s nearly two baserunners per inning he’s allowing! Mikolas has been consistently bad on the road since 2019.

On the flip side, the Giants have been heating up. Winners of five games in a row, they’ll send Logan Webb to the mound, who is always nasty at home and has only allowed 51 earned runs over his last 185.1 innings pitched at Oracle, good for a beautiful 2.48 ERA. This line opened at -132 and was quickly bet up to -145 and for good reason; The Giants are a value play all the way up to -185.