Pirates vs Brewers Prediction & Best Bets | Woodruff Returns to Form as Milwaukee Rolls

by | Aug 13, 2025 | mlb

Pirates vs Brewers Prediction & Best Bets | Woodruff Returns to Form as Milwaukee Rolls

The red-hot Milwaukee Brewers (74-44) look to extend their winning streak to 12 games as they host the struggling Pittsburgh Pirates (51-69) in Wednesday afternoon’s NL Central showdown at American Family Field. What makes this matchup particularly intriguing is Brandon Woodruff’s continued dominance since returning from injury, creating a significant pitching mismatch against a Pirates team that was just shut out 14-0 in Tuesday’s opener. With Milwaukee playing their best baseball of the season and the Pirates struggling to generate offense, this series finale offers several compelling betting opportunities.

Quick Picks:

  • Best Bet: Milwaukee Brewers -1.5 (-105) ★★★★☆
  • Top Prop: Brandon Woodruff Over 6.5 Strikeouts (-120) ★★★★☆
  • Value Play: Under 7.5 Runs (-115) ★★★☆☆

Pittsburgh Pirates vs Milwaukee Brewers Betting Odds & Latest Line Movement

Market Pittsburgh Pirates Milwaukee Brewers
Moneyline +185 -225
Run Line +1.5 (-115) -1.5 (-105)
Total Over 7.5 (-105) Under 7.5 (-115)

Opening Line: Milwaukee -215, Total 8.0

Sharp Money Analysis: Where Pro Bettors Are Placing Their Wagers

The line movement in this matchup has been minimal but telling. The moneyline has slightly increased from -215 to -225 on Milwaukee, indicating steady support for the heavily favored Brewers. More interestingly, the total has dropped from 8.0 to 7.5 despite Tuesday’s offensive explosion from Milwaukee. This suggests professional money is respecting the pitching matchup between Woodruff and Keller, two quality arms who could limit scoring despite Milwaukee’s recent offensive surge. The run line holding steady at -1.5 (-105) provides value for Brewers backers, as smart money typically doesn’t lay more than -120 on run lines regardless of the mismatch.

Pitching Matchup: Mitch Keller vs Brandon Woodruff – Who Has the Edge?

Pittsburgh Pirates: Mitch Keller (5-10, 3.86)

  • Better than his record indicates with solid 3.86 ERA across 137.2 innings
  • Respectable 107:37 K:BB ratio shows good command
  • 1.23 WHIP demonstrates ability to limit baserunners
  • Has allowed 3 or fewer earned runs in 14 of his last 16 starts
  • Struggled against Milwaukee earlier this season (5 ER in 5.1 IP)

Milwaukee Brewers: Brandon Woodruff (4-0, 2.29)

  • Outstanding since returning from injury with perfect 4-0 record
  • Elite 2.29 ERA and microscopic 0.65 WHIP show dominant form
  • Exceptional 45:6 K:BB ratio in 35.1 innings demonstrates pinpoint control
  • Averaging 11.5 K/9, highest rate of his career
  • Velocity has returned to pre-injury levels (95-97 mph fastball)
  • Has allowed just 1 home run all season

Advantage: Significant edge to Milwaukee. While Keller is a solid pitcher having a decent season, Woodruff is pitching at an elite level and has been virtually untouchable since his return. His combination of strikeout ability and control gives the Brewers a substantial advantage.

Bullpen Breakdown

The bullpen comparison heavily favors Milwaukee as well. The Brewers boast one of baseball’s most dominant relief corps, ranking 2nd in ERA (2.98) and 1st in strikeouts per nine innings (10.3). Trevor Megill has been outstanding as the closer with 28 saves, while Abner Uribe leads MLB with 31 holds. Even more impressive is their depth – Jared Koenig, Nick Mears, and Shelby Miller all provide quality middle relief options that bridge effectively to the late innings.

Pittsburgh’s bullpen has been serviceable but unspectacular, with a 4.12 ERA (17th in MLB). They’ve been overworked during this road trip, logging 9.2 innings in Tuesday’s blowout alone. Dennis Santana represents their only reliable high-leverage option with 7 saves and 13 holds. This significant disparity in bullpen quality and freshness creates another substantial edge for the Brewers.

Key Betting Trends & Team Statistics That Matter

  • Milwaukee has won 11 consecutive games, their second 11-game win streak since July
  • Brewers are an MLB-best 20-4 since the All-Star break
  • Pirates are just 29-51 against teams with winning records this season
  • Milwaukee is 8-3 against Pittsburgh this season, outscoring them 51-26
  • Brewers are 45-19 at American Family Field this season (best home record in NL)
  • Pirates are 22-36 on the road and have lost 7 of their last 9 away games
  • Brewers are 18-3 when Brandon Woodruff starts at home since 2023
  • Pirates have scored 3 or fewer runs in 9 of their last 12 games
  • Milwaukee is 42-16 when scoring first this season

William Contreras: Driving the Brewers’ Offensive Engine

William Contreras has been the catalyst for Milwaukee’s offensive explosion in the second half, hitting .342 with 8 home runs and 22 RBIs since the All-Star break. What makes him particularly dangerous against Pittsburgh is his outstanding performance in day games (.315 batting average) and his success against right-handed pitching like Keller (.286 with 17 homers). After going 2-for-4 with a double in Tuesday’s win, Contreras has multi-hit games in 6 of his last 9 contests. His ability to drive the ball to all fields and work deep counts makes him a difficult matchup for Keller, who tends to pitch to contact rather than overpower hitters.

American Family Field Factor: How the Venue Influences Today’s Game

American Family Field presents an interesting dynamic for today’s matchup. While the park ranks middle-of-the-pack for overall run scoring (0.976 park factor), it significantly boosts home run production (1.139 HR factor, 7th highest in MLB). This benefits the Brewers’ power-oriented lineup, especially with Woodruff’s ability to keep the ball in the park (just 1 HR allowed in 35.1 innings). The retractable roof will likely be closed for the afternoon game, creating consistent conditions that typically favor pitchers with good command – another advantage for Woodruff. The Brewers have masterfully leveraged their home park’s characteristics this season, going 45-19 at American Family Field while averaging 5.3 runs per game in home contests.

Expert Prediction & Best Bets for Pirates-Brewers Showdown

Primary Play: Milwaukee Brewers -1.5 (-105)

I’m taking the Brewers on the run line as my top play today. This is a classic situation where the moneyline price (-225) is too steep, but the run line offers excellent value at near even money. Milwaukee has been crushing opponents during their win streak, with 7 of their 11 consecutive victories coming by multiple runs. The combination of Woodruff’s dominance, a significant bullpen advantage, and the Pirates’ struggles to score runs (shut out last night) creates a perfect scenario for another comfortable Brewers win. The value at -105 is simply too good to pass up.

Strong Value Play: Brandon Woodruff Over 6.5 Strikeouts (-120)

Woodruff has been a strikeout machine since returning from injury, recording at least 7 Ks in four of his five starts. He faces a Pirates lineup that struck out 10 times last night and ranks 7th in MLB in strikeouts per game (8.65). Pittsburgh’s aggressive approach plays right into Woodruff’s strengths – his devastating fastball/changeup combination has generated a 45:6 K:BB ratio this season. With Woodruff likely to work at least 6 innings in this favorable matchup, I expect him to easily clear this strikeout threshold.

Worth Considering: Under 7.5 Runs (-115)

While the Brewers just exploded for 14 runs, I believe this game sets up as a lower-scoring affair. Woodruff has been nearly unhittable, and Keller is better than his record suggests. The Pirates’ offensive struggles (3 or fewer runs in 9 of their last 12 games) combined with Woodruff’s dominance should keep Pittsburgh’s scoring minimal. Even if Milwaukee puts up 4-5 runs, we’d still need significant Pirates production to threaten the over. The pitching matchup and recent Pirates offensive woes make the under an appealing option.

Player Props Worth Targeting in Today’s Matchup

Player Prop Odds Rating
Brandon Woodruff Over 6.5 Strikeouts -120 ★★★★☆
William Contreras Over 1.5 Total Bases +110 ★★★★☆
Christian Yelich To Record an RBI +130 ★★★☆☆
Mitch Keller Under 5.5 Strikeouts -115 ★★★☆☆
Bryan Reynolds Over 0.5 Hits -175 ★★★☆☆

Final Thoughts: Brewers’ Momentum Too Strong to Ignore

The Brewers are playing their best baseball of the season at the perfect time, establishing themselves as legitimate World Series contenders. Brandon Woodruff’s return has elevated their rotation from good to elite, complementing an offense that’s scoring runs in bunches. With Pittsburgh still reeling from Tuesday’s 14-0 blowout and struggling to generate consistent offense, I expect Milwaukee to handle business again today behind Woodruff’s strong pitching. The Pirates simply don’t have enough firepower to match up with this red-hot Brewers squad, especially with Milwaukee’s significant advantages in starting pitching, bullpen quality, and offensive production.

Score Prediction: Milwaukee Brewers 5, Pittsburgh Pirates 1

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