MLB Baseball Picks

Get the latest MLB picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around starting pitching matchups, bullpen form, advanced splits, and line value. From run line and total picks to full game breakdowns, this page brings together the most actionable MLB betting content on the board.

Our MLB Betting Tips section focuses on how to bet on MLB with proven handicapping strategy and in-depth betting education, helping bettors break down matchups, understand line movement, and build a smarter, more consistent approach to MLB wagering.

White Sox vs. Red Sox Best Bet 5/6/22

White Sox vs. Red Sox Best Bet 5/6/22

The unpredictable Vince Velasquez takes the hill against the Boston Red Sox vs Nathan Eovaldi who has been nasty this season. The BoSox are listed as -150 favorites. With Velasquez being a pitcher who could throw a perfect game and strike out 15 or get bombed and get the hook in the first inning, this game is as confusing as any! We’re here to help! Get our CWS/Bos pick here!

Tampa Bay at Seattle Total Pick

Tampa Bay at Seattle Total Pick

The Rays and Mariners go at Thursday night at T-Mobile Park in what will likely be a pitcher’s duel with McClanahan andl Ray on the hill! Get our TB/SEA prediction here!

NY Mets vs Philadelphia Phillies Moneyline Pick

NY Mets vs Philadelphia Phillies Moneyline Pick

The Mets bats have gone cold as they’ve scored three runs or less in three out of their last four games. It doesn’t get any easier for the NYM Thursday as they’ll face Phillies ace Aaron Nola! Get our Mets/Phillies betting prediction here!

Blue Jays vs. Guardians Lines & Picks

Blue Jays vs. Guardians Lines & Picks

Despite having a powerful offense, the Toronto Blue Jays have scored three runs or less in four of their last five games. The Guardians have been playing good baseball, winners of four of their last five games. Get our Tor/Cle prediction to win here!

Angels vs. Red Sox Odds & Predictions

Angels vs. Red Sox Odds & Predictions

The LAA had lost three out of their last four games before busting out for ten runs last night. The Red Sox now have lost three out of their last four. Neither team is playing lights out baseball. Get our Angels/Red Sox pick here!

Rangers vs. Phillies Picks & Analysis

Rangers vs. Phillies Picks & Analysis

One of 2022’s surprises has been the ability of the Texas Rangers to put up a bunch of runs! They’ve scored six or more run in two of their last three games and we don’t expect that to change playing in a hitters ballpark Wednesday! Get our Tex/Philly pick here!

MLB Betting Guide

New to betting on baseball? We've got you covered! Our comprehensive how to bet on baseball article explains all the different types of wagers offered at the sportsbooks including money lines, over/unders, run lines, parlays and more! Also get tips and strategies to increase your odds of beating the bookies!