Sproat’s 6.88 ERA meets Skubal’s dominance, but -226 asks for certainty this matchup can’t provide. Find out which way this one goes.
MLB Baseball Picks
Get the latest MLB picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around starting pitching matchups, bullpen form, advanced splits, and line value. From run line and total picks to full game breakdowns, this page brings together the most actionable MLB betting content on the board.
Our MLB Betting Tips section focuses on how to bet on MLB with proven handicapping strategy and in-depth betting education, helping bettors break down matchups, understand line movement, and build a smarter, more consistent approach to MLB wagering.
Braves vs. Nationals Prediction: Cavalli’s Walk Issues Meet Patient Atlanta Lineup
Cavalli’s 12 walks in 19.2 innings spell trouble against Atlanta’s disciplined lineup. The analysis is inside.
Joe Jensen’s April 22, 2026 MLB Recap: -1.1 Units on a 3-3 Card
Joe Jensen finished April 22, 2026 with a 3-3 record but posted a -1.1 unit loss as three two-unit defeats outweighed three two-unit wins. Despite strong side-play performance (6-2), the main card’s juice proved costly.
Phillies vs. Cubs Pick: Backhus’ Sinker Problem Meets Chicago’s Contact Surge
Backhus’ sinker generates just a 16.1% whiff rate against Chicago’s hot offense. Find out which way this one goes.
Padres vs. Rockies Prediction: Buehler’s Knuckleball Edge at Coors
Buehler’s strikeout edge matters more than the -163 price suggests at Coors Field. The analysis is inside.
White Sox vs. Diamondbacks Pick: Is the Run Line a Trap After Yesterday’s Slugfest?
Chase Field’s neutral environment changes how yesterday’s 11-run explosion should be read against today’s pitching matchup. The run line at +129 prices Arizona to cover easily after getting shelled at home. Find out which way this one goes.
Dodgers vs. Giants Prediction: Ohtani’s 0.50 ERA Meets Mahle’s 7.23 Struggle
Ohtani’s 0.72 WHIP against Mahle’s 1.93 WHIP shows two pitchers in different universes. The full read is inside.
Twins vs. Mets Best Bet: Holmes’ 1.96 ERA Against a 12-Game Skid
The bullpen gap between these teams is clear — Williams allowed seven runs while recording just four outs in his last three appearances. The moneyline at -163 prices this closer than the relief profiles and 12-game losing streak justify. The pick is inside.
Yankees vs. Red Sox Pick: Fried’s Elite Command Meets Suarez’s Hard Contact Issues
Fenway’s dimensions favor contact, but Suarez’s 0.351 xwOBA on his sinker spells trouble against this Yankees lineup. The full read is inside.
Blue Jays vs. Angels Pick: Soriano’s 0.28 ERA Meets Lauer’s 7.13 Collapse
Soriano’s 0.28 ERA against Lauer’s 7.13 collapse creates a starter gap the -163 moneyline undervalues. Find out which way this one goes.
MLB Baseball Picks
Padres vs. Giants Prediction: Vásquez’s Experience Edge Against McDonald’s 15-Inning Sample- Braves vs. Mariners Best Bet: Injury-Depleted Lineup Faces Road Test at T-Mobile
- White Sox vs. Angels Pick: Soriano’s 0.84 ERA Meets a Struggling Home Offense
- Dodgers vs. Astros Prediction: Yamamoto’s Elite Form Meets Houston’s Opener Strategy
- Brewers vs. Cardinals Best Bet: Patrick’s ERA Edge Meets Tight Road Number
- Padres vs. Giants Prediction: Vásquez’s Experience Edge Against McDonald’s 15-Inning Sample
- Braves vs. Mariners Best Bet: Injury-Depleted Lineup Faces Road Test at T-Mobile
- White Sox vs. Angels Pick: Soriano’s 0.84 ERA Meets a Struggling Home Offense
- Dodgers vs. Astros Prediction: Yamamoto’s Elite Form Meets Houston’s Opener Strategy
- Brewers vs. Cardinals Best Bet: Patrick’s ERA Edge Meets Tight Road Number
MLB Betting Guide
New to betting on baseball? We've got you covered! Our comprehensive how to bet on baseball article explains all the different types of wagers offered at the sportsbooks including money lines, over/unders, run lines, parlays and more! Also get tips and strategies to increase your odds of beating the bookies!