NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Arizona Cardinals vs. Chicago Bears Analysis & Prediction

Arizona Cardinals vs. Chicago Bears Analysis & Prediction

The Arizona Cardinals defense looked like a wet paper bag last weekend. Yeah, it was against a strong San Francisco 49ers team, but it was BAD. They’ll head to the Windy City to play the Chicago Bears as +4 underdogs in Week 16. Can they stop the Bears run game? Justin Fields looks to be setup for a “Field Day!” Get Loot’s AZ/Chi free pick here!

Washington Commanders at NY Jets Betting Pick

Washington Commanders at NY Jets Betting Pick

A pair of absolute train wrecks meet up in Week 16 when the Washington Commanders head to East Rutherford to take on the New York Jets as +3 underdogs. It would be fitting if this game ended in a 0-0 tie! Get Jay’s Wash/NYJ pick here!

Raiders vs. Chiefs Spread Bet – Week 16 Predictions

Raiders vs. Chiefs Spread Bet – Week 16 Predictions

The Las Vegas Raiders laid an absolute whooping on the Chargers last week. Can they stay hot against Andy Reid and the Kansas City Chiefs in Week 16? Oddsmakers don’t think so, as they’ve made KC a massive -9.5 favorite! Read Loot’s full game preview and get his LV/KC pick before placing your bets!

Seattle Seahawks vs. Tennessee Titans Analysis & Pick

Seattle Seahawks vs. Tennessee Titans Analysis & Pick

The Seattle Seahawks narrowly escaped victory on MNF vs. the Eagles last week. They’ll now take the trek to the south to play the Tennessee Titans as short -3 road favorites. They likely won’t be able to find the same success on the ground as they had vs. Philly, but whoever QB’s the Hawks should be able to pass on a weak Titans secondary. Who covers? Get Loot’s Sea/Phi point spread prediction here!

NFL Picks Week 16: Bills vs. Chargers

NFL Picks Week 16: Bills vs. Chargers

The Buffalo Bills head to tinsel town to play the Chargers as huge -11.5 road favorites after destroying the Cowboys last weekend. I can’t recall the last time I saw a favorite this big playing a road game on the opposite coast! Too many points, or not enough? Get Loot’s Buf/LAC pick here!

TNF Pick:  Saints vs. Rams Week 16 Betting Predictions

TNF Pick: Saints vs. Rams Week 16 Betting Predictions

Two teams that looked really good last week clash on Week 16’s Thursday Night Football when the New Orleans Saints play at the Los Angeles Rams as +4 underdogs. The Saints have been very poor at the betting window in 2023 with a 4-9-1 record against the spread. Can they keep it going vs. L.A., who is vying for a playoff spot? Get Loot’s NO/LAR TNF pick here!

NFL Picks: Chiefs vs. Patriots ATS Analysis & Prediction

NFL Picks: Chiefs vs. Patriots ATS Analysis & Prediction

A short few weeks ago, betting the New England Patriots as +8.5 underdogs against the Kansas City Chiefs would have been a preposterous proposition. In Week 15, not so much! Read Keith’s full game preview and get his KC/NE bet recommendation here!

SNF Picks: Ravens vs. Jaguars Spread & Total Predictions

SNF Picks: Ravens vs. Jaguars Spread & Total Predictions

The Week 15 Sunday Night Football game between the Baltimore Ravens and Jacksonville Jaguars should be a pretty good game. Both teams have lots of question marks going into the weekend though. Pick Keith’s brain and get his Balt/Jax prediction before placing your SNF wagers!