NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

NFL Picks Week 16: Bills vs. Chargers

NFL Picks Week 16: Bills vs. Chargers

The Buffalo Bills head to tinsel town to play the Chargers as huge -11.5 road favorites after destroying the Cowboys last weekend. I can’t recall the last time I saw a favorite this big playing a road game on the opposite coast! Too many points, or not enough? Get Loot’s Buf/LAC pick here!

TNF Pick:  Saints vs. Rams Week 16 Betting Predictions

TNF Pick: Saints vs. Rams Week 16 Betting Predictions

Two teams that looked really good last week clash on Week 16’s Thursday Night Football when the New Orleans Saints play at the Los Angeles Rams as +4 underdogs. The Saints have been very poor at the betting window in 2023 with a 4-9-1 record against the spread. Can they keep it going vs. L.A., who is vying for a playoff spot? Get Loot’s NO/LAR TNF pick here!

NFL Picks: Chiefs vs. Patriots ATS Analysis & Prediction

NFL Picks: Chiefs vs. Patriots ATS Analysis & Prediction

A short few weeks ago, betting the New England Patriots as +8.5 underdogs against the Kansas City Chiefs would have been a preposterous proposition. In Week 15, not so much! Read Keith’s full game preview and get his KC/NE bet recommendation here!

SNF Picks: Ravens vs. Jaguars Spread & Total Predictions

SNF Picks: Ravens vs. Jaguars Spread & Total Predictions

The Week 15 Sunday Night Football game between the Baltimore Ravens and Jacksonville Jaguars should be a pretty good game. Both teams have lots of question marks going into the weekend though. Pick Keith’s brain and get his Balt/Jax prediction before placing your SNF wagers!

Bears at Browns Betting Analysis & ATS Prediction | NFL Week 15

Bears at Browns Betting Analysis & ATS Prediction | NFL Week 15

The Bears have been playing much better since getting QB Justin Fields back and may provide a big challenge to the Browns. The sportsbooks have the right idea keeping this line at Cle -3 as the public is double fisting the home side. Read on to see where our prognosticator’s money is landing.

NY Giants at New Orleans Saints Free Pick

NY Giants at New Orleans Saints Free Pick

The New York Giants shocked the world Monday when they beat the Green Bay Packers straight up as big home underdogs. Can they keep the momentum rolling in Week 15 at +6 underdogs against a New Orleans Saints team that has crushed bettors with a 3-9 record against the spread? Get Jay’s NYG/NO point spread pick before placing your bets!

Minnesota Vikings at Cincinnati Bengals Analysis & Free Pick

Minnesota Vikings at Cincinnati Bengals Analysis & Free Pick

Did the Minnesota Vikings really win 3-0 last weekend? Or was that a REALLY bad dream? They’ll hit the road in Week 15 to take on the Cincinnati Bengals as +3.5 underdogs. At time of print, Justin Jefferson is listed as questionable to play. Get Darin’s Min/Cin point spread prediction here!