NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Baltimore vs. Cincinnati Wildcard Odds & Predictions

Baltimore vs. Cincinnati Wildcard Odds & Predictions

Oddsmakers have made the Cincinnati Bengals a -6.5 favorite in their Sunday AFC wildcard game with the Cincinnati Bengals. If you’ve been around the football betting industry long enough, a point spread of 6.5 raises red flags. Get Loot’s Bal/Cin pick here!

AFC Wildcard: Chargers vs. Jaguars Pick ATS

AFC Wildcard: Chargers vs. Jaguars Pick ATS

Two very similar teams meetup during Wildcard Weekend when the 10-7 Los Angeles Chargers head to Jacksonville to take on the 9-8 Jaguars. Both teams possess high powered offenses while both defensive units are vulnerable to both the run and the pass. Oddsmakers have made the Bolts a short -1 road fav. Who gets the money? Get Loot’s LA/Jax pick here!

Seattle Seahawks vs. San Francisco 49ers Point Spread Pick

Seattle Seahawks vs. San Francisco 49ers Point Spread Pick

The Seattle Seahawks barely got by the Los Angeles Rams last week to squeeze into the playoffs. The Hawks have a tough road ahead of them as they’ll have to head south to Levi’s Stadium to take on the red-hot San Francisco 49ers who have an advantage at every position except for cornerback. The bookies have made San Fran a heavy -10.5 favorite. Who covers the spread? Get out Sea/SF Wildcard prediction here!

Patriots vs. Bills Point Spread – Free Pick ATS

Patriots vs. Bills Point Spread – Free Pick ATS

The Buffalo Bills return to the field after the tragic event on MNF in which the world watched Damar Hamlin suffer a serious injury. Will the team come out flat? Will Buffalo come together to play hard for their fallen teammate? Will the injury factor into the game at all? Get Keith’s take and NE/Buf pick here!

Arizona Cardinals vs. San Francisco 49ers

Arizona Cardinals vs. San Francisco 49ers

Expect a maximum effort from the San Francisco 49ers this week as they’re fighting for a number one seed in the upcoming playoffs. But can they cover a massive two touchdown point spread? Get Loot’s AZ/SF pick here!