NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

49ers vs. Bears Analysis & Spread Prediction

49ers vs. Bears Analysis & Spread Prediction

Bettors should approach Week 1 with caution, as we don’t really have a strong take on what will happen with any team until we see them play, analyze and make assessments. The Niners vs. Bears game with a 7-point spread is sketchy at best, but Loot will give you his best shot at calling a winner.

Lay the Points: Steelers vs. Bengals ATS Bet

Lay the Points: Steelers vs. Bengals ATS Bet

The Pittsburgh Steelers start “Life without Ben Roethlisberger” against the Cincinnati Bengals in Week 1 against Joe Burrow, who has beaten them by double digits three times in a row. Get Jay’s Pit/Cin pick ATS before placing your bets!

Chiefs vs. Cardinals Spread & Total Predictions

Chiefs vs. Cardinals Spread & Total Predictions

With a bunch of new players on offense (JuJu Smith-Schuster/Marquez Valdez-Scantling/Skyy Moore) and being on the road, can the Kansas City Chiefs cover a -4.5 point spread against the Arizona Cardinals? Get Ted’s KC/AZ prediction here!

Cleveland Browns vs. Carolina Panthers Week 1 Predictions

Cleveland Browns vs. Carolina Panthers Week 1 Predictions

In one of the more surprising point spreads of Week 1 NFL, the Carolina Panthers are favored over the Cleveland Browns at -2. Cleveland’s offseason has been fairly ugly, but enough to be an underdog vs. a lesser team? Read Jay’s Week One Browns vs. Panthers preview and get his Cle/Car prediction here!

New Orleans Saints vs. Atlanta Falcons Week 1 Play

New Orleans Saints vs. Atlanta Falcons Week 1 Play

Jay thinks line play will be the difference in Sunday’s Week 1 matchup between the New Orleans and Atlanta Falcons. One has to wonder if Marcus Mariota can lead a team as well, as he’s failed to do so numerous times in his career. Get our NO/Atl point spread pick before placing your bets!

2021 NFL Picks That Paid

2021 NFL Picks That Paid

Kevin West points out which teams won big and lost big in different situations during the 2021 NFL football season.

New York Giants vs. New York Jets Betting Predictions

New York Giants vs. New York Jets Betting Predictions

With Zach Wilson hurt, the Jets still have decisions to make at the quarterback position. Could this variable be enough to give them a cover? They also have a coach that doesn’t like to lose. Could the NYJ at -3 be the best bet of NFLX? Get Dan’s NYG/NYJ pick here!