NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Falcons vs. 49ers Point Spread – Free Pick 12/19/21

Falcons vs. 49ers Point Spread – Free Pick 12/19/21

The Week 15 game between the Atlanta Falcons vs. San Francisco 49ers is one in which the whole world will likely be backing the Niners, yet the Falcons will find a way to cover. Don’t get caught up in this sucker bet! Get Loot’s Atl/SF winner here!

Arizona Cardinals vs. Detroit Lions Predictions ATS

Arizona Cardinals vs. Detroit Lions Predictions ATS

At this point in the season, one has to wonder how motivated the fledgling Detroit Lions will be with only one win under their belt. They come into Week 15 as unprecedented +13.5 home underdogs vs. an Arizona Cardinals team that COULD destroy them if motivated and healthy. Get Loot’s Az/Det prediction here!

Carolina Panthers vs. Buffalo Bills Prediction ATS

Carolina Panthers vs. Buffalo Bills Prediction ATS

Carolina juggled quarterbacks last week and looked like a team headed for the septic tank. The Bills played decent, but got bested by Tom Terrific. This Week 15 Panthers vs. Bills game looked to be one-sided, but can Buffalo cover this huge double digit spread? Get Jay’s Car/Buf pick before placing your wagers!