NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

NFC Championship Predictions: 49ers vs. Rams

NFC Championship Predictions: 49ers vs. Rams

The San Francisco 49ers and Los Angeles Rams meet up for the third time this season on Sunday at SoFi Stadium with the winner moving on to the NFC Championship Game. The Niners have taken both games this season. Is the third time a charm? Get Loot’s SF/LAR prediction here!

Bills vs. Chiefs Odds & Prediction ATS 1/23/21

Bills vs. Chiefs Odds & Prediction ATS 1/23/21

Two Super Bowl worthy teams meet up in KC Sunday evening when Josh Allen and the Buffalo Bills play Patrick Mahomes and the Kansas City Chiefs. The bookies have K. City as 3-point favorites. Get Jay’s Buf/KC prediction here!

Cincinnati Bengals vs. Tennessee Titans Betting Pick

Cincinnati Bengals vs. Tennessee Titans Betting Pick

The Tennessee Titans have made “winning ugly” an art form. They get the Cincinnati Bengals at home in the Divisional Playoffs and oddsmakers have installed them as -3.5 favorites. There’s been no official word on Derrick Henry (at time of print), but that isn’t influencing this Handicapper’s opinion! Get Jay’s Cin/Ten prediction here!

Arizona Cardinals vs. Los Angeles Rams Prediction 1/17/22

Arizona Cardinals vs. Los Angeles Rams Prediction 1/17/22

Two of the most inconsistent NFL teams with great records go at it Sunday evening at Sofi Stadium when the Arizona Cardinals visit the Los Angeles Rams as four-point underdogs. With Arizona grabbing two key numbers, they have some great wagering value!