NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Broncos vs. Chargers Odds & Best Bet

Broncos vs. Chargers Odds & Best Bet

Have the Broncos thrown in the towel? They got absolutely SMASHED by the Bills last week. Can Anthony Lynn’s decision-making be trusted with your hard-earned money? Get Loot’s Den/LAC betting prediction!

Cleveland Browns vs. New York Jets Analysis & Prediction

Cleveland Browns vs. New York Jets Analysis & Prediction

Somehow, the Jets beat the Rams on the road last week. After looking at going winless this season, could it be possible that they put together a 2-game win streak? Or will they go back to being a wet paper bag? Get Zman’s Cle/NYJ pick here!

Rams vs. Seahawks Odds & Picks

Rams vs. Seahawks Odds & Picks

The Los Angeles Rams laying an egg at home last week vs. the Jets was absolutely unfathomable! The Seahawks almost got beat by the Washington Football Team last week as well. We assume that both teams overlooked their opponents. That won’t be the case in Week 16 when these teams meet at Lumen Field in Seattle. Get Loot’s LAR/SEA pick here!

San Francisco 49ers vs. Arizona Cardinals Week 16 Pick

San Francisco 49ers vs. Arizona Cardinals Week 16 Pick

Two teams that started out with huge hopes and now have broken dreams meet up in the cactus state Saturday. Both of these teams have been tough to predict all season long (with regards to the spread). Get Loot’s SF/AZ spread prediction here!

Miami Dolphins vs. Las Vegas Raiders Pick ATS

Miami Dolphins vs. Las Vegas Raiders Pick ATS

The Week 16 NFL matchup between the Miami Dolphins and Las Vegas Raiders is one of the tougher games of the week to pick. Whenever you encounter a game like this, it’s always best to pass. However, if you must bet it, Loot gives you his best opinion on which team will cover the 2.5!

Tampa Bay Buccaneers vs. Detroit Lions Pick 12/26/20

Tampa Bay Buccaneers vs. Detroit Lions Pick 12/26/20

After dropping two close games to the Rams and Chiefs, the Bucs have won two in a row and with a win this week can secure a playoff spot. They hit the road to take on the Lions who struggling mightily last week against the Titans getting lit up for 46 points. Is there any value in backing the home side getting 8.5 points?

Minnesota at New Orleans Pick 12/25/20

Minnesota at New Orleans Pick 12/25/20

The Vikings may have the work cut out for them on Friday when they face the Saints number one ranked home rush defense. New Orleans QB Drew Brees should also be better after getting a game under his belt after missing time. Read on to get Lott’s suggested bet.

Carolina Panthers vs. Washington Football Team Pick

Carolina Panthers vs. Washington Football Team Pick

The Washington Football Team almost pulled off an upset Sunday vs. the Seahawks. Despite the loss (and many losses this season for that matter), the team has been a point spread covering machine at 8-5-1. This game could be a slog and won’t be easy to predict. Get Jay’s take here!

Week 16 Picks: Philadelphia Eagles vs. Dallas Cowboys

Week 16 Picks: Philadelphia Eagles vs. Dallas Cowboys

After a disastrous mid-season, the Dallas Cowboys look to be on the rebound after putting up 41 points against the Niners on Sunday. Surprisingly, they come in as +1 home underdogs in Week 16 vs. Jalen Hurts and the Philadelphia Eagles. Get Jay’s Phi/Dal pick here!

Atlanta Falcons vs. Kansas City Chiefs Pick ATS

Atlanta Falcons vs. Kansas City Chiefs Pick ATS

The Kansas City Chiefs continue to roll at 13-1 and are coming off a huge road win in which they pretty much dominated the New Orleans Saints for the whole game. This week they head back to Arrowhead as -11 favs to take on the Atlanta Falcons. Can the Dirty Birds hang with them? Get Jay’s prediction here!