NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

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Tennessee Titans vs. Buffalo Bills Pick

Tennessee Titans vs. Buffalo Bills Pick

Keith Franks breaks down the recent performance of the Buffalo Bills and the Tennessee Titans. The Titans currently sit as only 3.5 point favorites with a 3-1 record while the Bills are playing for the right to approach 500. Keith gives his pick and game prediction.

Pittsburgh Steelers vs Atlanta Falcons Pick

Pittsburgh Steelers vs Atlanta Falcons Pick

Bob Clark sees this game close and high scoring right from the beginning. Both offenses have weapons and both defenses are lacking. The Steelers rank 26th in the NFL in scoring defense and the Falcons are worse at 30th. Bob breaks down the game and offers a side play but also has a strong over/under pick.

Minnesota Vikings vs Philadelphia Eagles Pick

Minnesota Vikings vs Philadelphia Eagles Pick

Coming into last week’s game, the Titans were a running team, coming in second to last in the NFL in pass attempts. In the win over the Jaguars, they ran the ball 35 times and had only 21 attempts in the air. This week they flipped the script, throwing it 43 times and running it 22 times. Which team should the Eagles prepare for next Sunday and does it matter. Rick Wise looks at the 3 point spread and gives his week 5 pick.

New England Patriots host Indianapolis Colts: Pick & Prediction

New England Patriots host Indianapolis Colts: Pick & Prediction

With a win to bring the club to 500 and some key pieces returning for week 5, the New England Patriots suddenly feel like a team with momentum. The sportsbook’s line reflects that with a Pats -10 spread at home. Mike Mann makes his NFL week 5 pick here and breaks down injuries, match-ups and team trends.

Kansas City Chiefs vs. Denver Broncos Pick

Kansas City Chiefs vs. Denver Broncos Pick

Kevin West: “I wasn’t surprised to learn that the public is siding with KC, as the media is blasting Pat Mahomes mania after the barrage of touchdowns he’s thrown. What did surprise me was that only 34% of bettors are backing the Broncs. Within that 34% are sharp bettors/wiseguys with ear to ear smiles.” Kevin breaks down the Monday game where sportsbooks currently have the Chiefs as 5 point favorites.

San Francisco 49ers vs Los Angeles Chargers Pick

San Francisco 49ers vs Los Angeles Chargers Pick

Last season, the Niners were flat on their backs until Jimmy G showed up and immediately put the Niners on the right path. Without him, it’s only fair to wonder if we’ll see the same team we saw early last season. Sportsbooks are hanging a -10 on the Chargers. For those of us who backed San Fran last year, it doesn’t feel like enough. Do the Chargers have the killer instinct to put a hobbled Niner team down?

Seattle Seahawks vs. Arizona Cardinals Pick

Seattle Seahawks vs. Arizona Cardinals Pick

Poor QB play has made the Cardinals’ cast ineffective. David Johnson is sitting at 116 yards rushing and hasn’t made an impact. Larry Fitzgerald is at 113 yards. Young ball-catchers and former Texas A&M products Christian Kirk and Ricky Seals-Jones are nice weapons, but there is nothing nice about 20 points of scoring through three games. Will the birds’ offense remain grounded on Sunday? Loot makes his NFL pick.

Cleveland Browns vs. Oakland Raiders Pick

Cleveland Browns vs. Oakland Raiders Pick

Online sportsbooks have the Raiders -2.5. Many people will look at this game and measure the teams against their expectations, as opposed to the match up against each other. By an expectations-standard, the Browns have been far-better than the Raiders, but are they better than the Raiders overall? That’s a trickier question. Let’s try to answer that question and make our pick.

Houston Texans vs. Indianapolis Colts Pick

Houston Texans vs. Indianapolis Colts Pick

Bob Clark reviews the first three games for Indianapolis and Houston and focuses on strength of schedule before making his NFL pick. Bob also has a total play for this Sunday game.

Philadelphia Eagles vs. Tennessee Titans Pick

Philadelphia Eagles vs. Tennessee Titans Pick

Bob Clark anticipates a hard nosed, low scoring affair between two average offenses and two amazing defenses. Bookmakers have the over/under set at 41 points. Read Bob’s pick on the spread and total play.