NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Arizona Cardinals vs. Detroit Lions Predictions ATS

Arizona Cardinals vs. Detroit Lions Predictions ATS

At this point in the season, one has to wonder how motivated the fledgling Detroit Lions will be with only one win under their belt. They come into Week 15 as unprecedented +13.5 home underdogs vs. an Arizona Cardinals team that COULD destroy them if motivated and healthy. Get Loot’s Az/Det prediction here!

Carolina Panthers vs. Buffalo Bills Prediction ATS

Carolina Panthers vs. Buffalo Bills Prediction ATS

Carolina juggled quarterbacks last week and looked like a team headed for the septic tank. The Bills played decent, but got bested by Tom Terrific. This Week 15 Panthers vs. Bills game looked to be one-sided, but can Buffalo cover this huge double digit spread? Get Jay’s Car/Buf pick before placing your wagers!

Rams vs. Cards Week 14 Odds & Pick Against the Spread

Rams vs. Cards Week 14 Odds & Pick Against the Spread

Despite the Arizona Cardinals missing players recently with injury, the team still has winning record and has been crushing it against the spread. The Rams have a winning record, but they have crushed bettors at the windows. Who covers this one? Get Keiths LAR/AZ pick here!

Raiders at Chiefs Odds & Pick ATS 12/12/21

Raiders at Chiefs Odds & Pick ATS 12/12/21

When it comes to NFL betting, you want to avoid laying big numbers as it’s not a winning formula. In the case of Week 14’s Las Vegas Raiders vs. Kansas City Chiefs matchup, you may want to throw that advice out the window! Get Darin’s LV/KC pick here!