NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Jacksonville at New England Best Bet 1/2/22

Jacksonville at New England Best Bet 1/2/22

One of the biggest point spreads of the year goes off in Week 17 when the hapless Jacksonville Jaguars head North to take on the New England Patriots as massive +15.5 underdogs. Get Loot’s Jax/NE prediction here!

Arizona at Dallas Week 17 Odds & Picks

Arizona at Dallas Week 17 Odds & Picks

It’s tough to fathom betting on the Arizona Cardinals at +5.5 with as bad as they’ve looked recently. Especially after the Dallas Cowboys just put up a 50 burger on national TV. But as you probably are aware, oddsmakers are notorious for being right more than the bettors, so this should raise eyebrows! Get Loot’s AZ/Dal prediction here!

Miami Dolphins vs. New Orleans Saints MNF Predictions

Miami Dolphins vs. New Orleans Saints MNF Predictions

Two teams playing really good football meet up for Week 16 Monday Night Football when the Miami Dolphins head to the Big Easy to take on the New Orleans Saints, who are coming off an amazing shutout on the road against Tom Brady and the Tampa Bay Buccaneers. Get Keith’s Mia/N.O. prediction here!

Chicago Bears at Seattle Seahawks Prediction ATS

Chicago Bears at Seattle Seahawks Prediction ATS

Then Chicago Bears haven’t been winning at all, yet their Week 16 point spread of +6.5 implies that bookies think they can cover the spread vs. the Seattle Seahawks. Check out Darin’s preview and get his Chi/Sea pick here!