NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

49ers vs. Cowboys Wildcard Pick

49ers vs. Cowboys Wildcard Pick

Two NFL teams who have been wildly inconsistent this season meet up Sunday at Jerry’s World when the San Francisco 49ers play the Dallas Cowboys. Get Jay’s SF/Dal NFC Wildcard prediction here!

Eagles vs. Bucs Wild Card Odds & Pick Against the Spread

Eagles vs. Bucs Wild Card Odds & Pick Against the Spread

The Philadelphia Eagles and Tampa Bay Buccaneers go out at Sunday afternoon with the Bucs coming in as a huge nine-point favorites, and for good reason! Tom Brady is going to exploit the Eagles! Get Keith’s full game preview and Phi/TB pick here!

Wild Card Picks: Steelers vs. Chiefs 1/16/22

Wild Card Picks: Steelers vs. Chiefs 1/16/22

Despite the Kansas City Chiefs having boasting a 12-5 record straight up, they were losers at the betting window this season, going a meager 8-9 against the spread. Can they cover a double-digit point spread in the AFC Wildcard game? Get Loot’s prediction here!

Las Vegas Raiders vs. Cincinnati Bengals Pick ATS

Las Vegas Raiders vs. Cincinnati Bengals Pick ATS

Letdowns happen in college football. Do they take place in the NFL? We’ll find out, as the Raiders hit the road after a ridiculously exciting Sunday Night Football game in which they bested the Chargers by field goal with no time left. Get Loot’s LV/Cin prediction here!

Seattle Seahawks vs. Arizona Cardinals Spread Pick 1/9/22

Seattle Seahawks vs. Arizona Cardinals Spread Pick 1/9/22

The Arizona Cardinals sure don’t feel like an 11-5 NFL team, however, they sure looked like one last week, ringing in the New Year with a huge road win against the Dallas Cowboys at Jerry World. Can they keep it rolling vs. a Seahawks team featuring Russell Wilson who likely has one foot out the door? Get Keith’s Sea/Az pick here!

Green Bay Packers at Detroit Lions Predictions 1/9/22

Green Bay Packers at Detroit Lions Predictions 1/9/22

With neither team having anything to play for, the Green Bay Packers vs. Detroit Lions Week 18 matchup might be one worth passing on. Fishy point spreads usually provide fishy results. See how Ted is betting the GB/Det game here!