The Niners are 6-0, but this offense looks a lot less effective since losing Kyle Juszczyk. On the other side of the ball, the Panthers have been successful despite losing Cam Newton and have played exceptionally well on defense. Can anybody slow down Christian McCaffrey? There may be an upset brewing in the Bay Area! Betting the favorite here at -5.5 will be very risky in a game where Carolina has a legit shot to win straight up.









