Our office is divided on the Week 6 NFL matchup between the Vikings/Colts! Get Jay’s Min/Car take here!
NFL Football Picks
Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.
Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.
TNF Picks: Tampa Bay Buccaneers vs. Philadelphia Eagles
Just when you were ready to write-off the 2021 Philadelphia Eagles team, they go into Carolina and beat up the red-hot Panthers. This week, they’re featured on Thursday night football and return to Lincoln Financial Field to host the Tampa Bay Buccaneers as +7 home underdogs. And a live dog they are! Get Loot’s Week 6 TNF TB/Phi pick here!
MNF Picks: Indianapolis Colts vs. Baltimore Ravens
Oddsmakers are sharp and point spreads are never as easy as they look. The Week 6 Monday Night Football game between the Colts and Ravens should be approached with caution. Our eyes tell us the Ravens will blow out a weak Indianapolis team. The bookies think otherwise. See how Loot is betting Week 5 MNF here!
Buffalo Bills vs. Kansas City Chiefs Spread Prediction
The Chiefs have sucked ass against the spread this season and that doesn’t look to change on Sunday night against a Bills team that looks like Super Bowl contenders. Get our Week 5 SNF pick here!
Packers vs. Bengals Odds & Predictions
The fishiest spread of the 2021 NFL season goes off Sunday when the Green Bay Packers visit Paul Brown Stadium as +3 underdogs. It’s usually best to avoid or bet with the fishy line, however in this case, Ted is rolling with it! Get his GB/Cin pick here!
49ers vs. Cardinals Point Spread – Free Pick ATS
Who had the Arizona Cardinals blowing out the Rams last week? Not us! Can they keep it going against a hungry San Francisco 49ers team? Find out here!
Browns vs. Chargers Odds & Predictions 10/10/21
Two NFL teams playing good football and winning games meet up in the Week 5 when the Cleveland Browns travel to Tinseltown to play the Los Angeles Chargers. This is the toughest spread on this week’s card.
Lay the Points: Chicago Bears vs. Las Vegas Raiders Pick
Justin Fields looked much more comfortable last week vs. the Lions. Expect John Gruden to bring heavy pressure this week. Get Loot’s Chi/LV pick here!
Giants vs. Cowboys Betting Pick ATS
The Dallas Cowboys have covered the spread in every game this season. Can they keep it up in Week 5 against the New York Giants in a game with a fishy point spread of only -7? Find out here!
New Orleans vs. Washington Spread Pick
This may be the easiest ATS pick of Week Five! Washington brings pressure. Jameis Winston sucks under pressure. The writing is on the wall!
College Football Picks
Miami vs Indiana Expert Picks & Best Bets for Monday, January 19th, 2026- Oregon vs. Indiana Prediction: College Football Playoff Semifinal 1/9
- Miami vs. Ole Miss Prediction: Sharp Money Backs Hurricanes in Fiesta Bowl
- Arizona vs. SMU Predictions: Will the Wildcats’ Five-Game Streak Hold?
- ReliaQuest Bowl Betting Preview: Expert Predictions & Best Bet
- Miami vs Indiana Expert Picks & Best Bets for Monday, January 19th, 2026
- Oregon vs. Indiana Prediction: College Football Playoff Semifinal 1/9
- Miami vs. Ole Miss Prediction: Sharp Money Backs Hurricanes in Fiesta Bowl
- Arizona vs. SMU Predictions: Will the Wildcats’ Five-Game Streak Hold?
- ReliaQuest Bowl Betting Preview: Expert Predictions & Best Bet
