NFL Football Picks

Get the latest NFL picks, predictions, and betting analysis from Predictem’s handicappers, with coverage built around matchup edges, situational spots, injury impact, and line value. From point spread and total picks to full game breakdowns, this page brings together the most actionable NFL betting content on the board.

Our NFL Betting Tips section is built around NFL betting strategy and education, giving bettors a clear framework for how to bet on football, interpret line movement, and attack the market with discipline. If you’re serious about finding value each week, keep this page in your rotation.

Seattle vs. New Orleans Week 5 Betting Predictions

Seattle vs. New Orleans Week 5 Betting Predictions

With the Seattle Seahawks playing well against the Lions and the Saints coming back from overseas we may just have the perfect storm for Seattle to cover the spread (or win) a game they wouldn’t normally cash in on. Get Loot’s Week 5 Sea/N.O. pick here!

Barking Dog Alert: Dolphins vs. Jets

Barking Dog Alert: Dolphins vs. Jets

Can “Teddy Two-Gloves” take over the reigns and lead the Miami Dolphins to victory in Week 5? Oddsmakers have the Phins set as -3.5 road favorites against the Jets who should gain momentum each week with Zach Wilson back behind center. Get Loot’s Mia/NYJ pick here!

Houston at Jacksonville Odds & Picks

Houston at Jacksonville Odds & Picks

In all candidness, the Week 5 game between the Houston Texans and Jacksonville Jaguars is one you shouldn’t bet. There are too many question marks with both of these teams at this point in the season. Our office is split on the contest as well! Get Loot’s Hou/Jax pick here!

Tennessee Titan vs. Washington Commanders Week 5 Pick

Tennessee Titan vs. Washington Commanders Week 5 Pick

Oddsmakers have set the Week 5 game between the Tennessee Titans and Washington Commanders at Ten -2.5. This tells us they think that Washington covers this game. We think otherwise, as Washington’s defense is porous at best and we don’t think the Washington defense can stop the Big Dog who is primed to eat! Get Loot’s Ten/Wash pick here!

Pittsburgh Steelers vs. Buffalo Bills Betting Pick

Pittsburgh Steelers vs. Buffalo Bills Betting Pick

Bug meets windshield in Week 5 when the Pittsburgh Steelers and their fledgling offense head to Highmark Stadium to take on the high-flying Buffalo Bills on Sunday. The books have made the Bills huge -14 favorites and the general betting public is biting to the tune of 57% which has led to some sportsbooks moving the betting line up a half point to -14.5. Get Jay’s Pit/Buf pick here!

LA Chargers vs. Cleveland Browns ATS Prediction

LA Chargers vs. Cleveland Browns ATS Prediction

The Los Angeles Chargers looked really good last week, however, it was against the lowly Houston Texans who has a very poor defense. The Browns won the on the road as well. Who covers the spread in this battle of teams will excellent running backs? Get Loot’s LAC/Cle bet recommendation before placing your wager!

TNF: Colts vs. Broncos Point Spread Pick

TNF: Colts vs. Broncos Point Spread Pick

The Denver Broncos lost star running back Javonte Williams for the season, yet are favored by -3.5 at home against the poor playing Indianapolis Colts. Get Loot’s take and Ind/Den betting prediction here!